SCHEMBL180928

SCHEMBL180928

C[C@@H](OP(=O)(OC[C@H]1O[C@@H](n2cnc3c(=O)[nH]c(N)nc32)[C@H](O)[C@@H]1O)OP(=O)(O)O)[C@H](O)[C@H](O)[C@@H](O)C=O

nearest known ligand 0.61

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NT5E P21589 1/20 0.61
TGM2 P21980 1/20 0.59
IMPDH2 P12268 6/20 0.56
FUT5 Q11128 1/20 0.56
KRAS P01116 8/20 0.55
IMPDH1 P20839 2/20 0.54
HINT1 P49773 1/20 0.53
TAS1R3 Q7RTX0 1/20 0.52
TAS1R1 Q7RTX1 1/20 0.52
P2RY2 P41231 1/20 0.52
P2RY4 P51582 1/20 0.52
P2RY6 Q15077 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1235770 1.00 NT5E (0.61) NT5ETGM2IMPDH2FUT5KRAS
SCHEMBL8669732 0.93 NT5E (0.59) NT5ETGM2IMPDH2FUT5KRAS
SCHEMBL1269745 0.92 NT5E (0.61) NT5ETGM2IMPDH2FUT5KRAS
SCHEMBL6027526 0.89 NT5E (0.61) NT5ETGM2IMPDH2FUT5KRAS
SCHEMBL1697432 0.89 NT5E (0.61) NT5ETGM2IMPDH2FUT5KRAS
L-Fucose SCHEMBL18992533 0.89 TGM2 (0.67) NT5ETGM2IMPDH2FUT5KRAS
L-Fucose SCHEMBL20607674 0.89 TGM2 (0.67) NT5ETGM2IMPDH2FUT5KRAS
Glucuronic Acid SCHEMBL6046180 0.87 TGM2 (0.66) NT5ETGM2IMPDH2FUT5KRAS
Glucuronic Acid SCHEMBL27957333 0.87 TGM2 (0.66) NT5ETGM2IMPDH2FUT5KRAS
Glucuronic Acid SCHEMBL5941537 0.87 TGM2 (0.66) NT5ETGM2IMPDH2FUT5KRAS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 246 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025015168-A1 CELL-FREE PRODUCTION OF HUMAN MILK OLIGOSACCHARIDES (HMOS) Debut Biotechnology, Inc. (US) 2025-01-16 WO claimed
EP-1426441-B1 ALPHA-1,2-FUCOSYL TRANSFERASE AND DNA ENCODING THE SAME KYOWA HAKKO BIO CO LTD (JP) 2010-05-19 EP claimed
US-6875591-B1 Process for producing GDP-fucose KYOWA, HAKKO KOGYO CO., LTD. (JP) 2005-04-05 US claimed
US-20040219553-A1 Alpha-1,2-fucosyltransferase and dna encoding the same KYOWA HAKKO KOGYO CO. LTD. (JP) 2004-11-04 US claimed
EP-1426441-A1 ALPHA-1,2-FUCOSYL TRANSFERASE AND DNA ENCODING THE SAME KYOWA HAKKO KOGYO CO., LTD. (JP) 2004-06-09 EP claimed
US-20020068331-A1 Production of fucosylated carbohydrates by enzymatic fucosylation synthesis of sugar nucleotides; and in situ regeneration of GDP-fucose WONG CHI-HUEY (US) 2002-06-06 US claimed
US-6319695-B1 FORMING A GLYCOSIDE BOND BY ETHERIFICATION AND CIRCULATION THE SCRIPPS RESEARCH INSITUTE 2001-11-20 US claimed
EP-1076096-A1 Process for producing GDP-fucose KYOWA HAKKO KOGYO CO., LTD. (JP) 2001-02-14 EP claimed
EP-0642526-A4 PRODUCTION OF FUCOSYLATED CARBOHYDRATES BY ENZYMATIC FUCOSYLATION SYNTHESIS OF SUGAR NUCLEOTIDES; AND IN SITU REGENERATION OF GDP-FUCOSE. SCRIPPS RESEARCH INST (US) 1996-04-10 EP claimed
EP-0642526-A1 PRODUCTION OF FUCOSYLATED CARBOHYDRATES BY ENZYMATIC FUCOSYLATION SYNTHESIS OF SUGAR NUCLEOTIDES; AND IN SITU REGENERATION OF GDP-FUCOSE THE SCRIPPS RESEARCH INSTITUTE (US) 1995-03-15 EP claimed
WO-1993008205-A1 PRODUCTION OF FUCOSYLATED CARBOHYDRATES BY ENZYMATIC FUCOSYLATION SYNTHESIS OF SUGAR NUCLEOTIDES; AND IN SITU REGENERATION OF GDP-FUCOSE THE SCRIPPS RESEARCH INSTITUTE (US) 1993-04-29 WO claimed
US-20260022384-A1 ASPARAGINE SYNTHETASE INHIBITORS AND USES THEREOF OSPEDALE SAN RAFFAELE S.R.L. (IT) 2026-01-22 US disclosed
US-12491217-B2 Compositions and methods for promoting healthy neural development in an unborn baby THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-12-09 US disclosed
WO-2025015168-A1 CELL-FREE PRODUCTION OF HUMAN MILK OLIGOSACCHARIDES (HMOS) Debut Biotechnology, Inc. (US) 2025-01-16 WO disclosed
US-20230181621-A1 ASPARAGINE SYNTHETASE INHIBITORS AND USES THEREOF OSPEDALE SAN RAFFAELE S.R.L. (IT) 2023-06-15 US disclosed
EP-0642526-B1 PRODUCTION OF FUCOSYLATED CARBOHYDRATES BY ENZYMATIC FUCOSYLATION SYNTHESIS OF SUGAR NUCLEOTIDES; AND IN SITU REGENERATION OF GDP-FUCOSE SCRIPPS RESEARCH INST (US) 1998-12-23 EP disclosed
EP-0870841-A1 PROCESSES FOR PRODUCING SUGAR NUCLEOTIDES AND COMPLEX CARBOHYDRATES KYOWA HAKKO KOGYO CO., LTD. (JP) 1998-10-14 EP disclosed
EP-0642526-A4 PRODUCTION OF FUCOSYLATED CARBOHYDRATES BY ENZYMATIC FUCOSYLATION SYNTHESIS OF SUGAR NUCLEOTIDES; AND IN SITU REGENERATION OF GDP-FUCOSE. SCRIPPS RESEARCH INST (US) 1996-04-10 EP disclosed
EP-0642526-A1 PRODUCTION OF FUCOSYLATED CARBOHYDRATES BY ENZYMATIC FUCOSYLATION SYNTHESIS OF SUGAR NUCLEOTIDES; AND IN SITU REGENERATION OF GDP-FUCOSE THE SCRIPPS RESEARCH INSTITUTE (US) 1995-03-15 EP disclosed
WO-1993008205-A1 PRODUCTION OF FUCOSYLATED CARBOHYDRATES BY ENZYMATIC FUCOSYLATION SYNTHESIS OF SUGAR NUCLEOTIDES; AND IN SITU REGENERATION OF GDP-FUCOSE THE SCRIPPS RESEARCH INSTITUTE (US) 1993-04-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230181621-A1 ASPARAGINE SYNTHETASE INHIBITORS AND USES THEREOF ASNS, GLS, GLS2 NT5E 416/4885TGM2 116/4885IMPDH2 390/4885
US-20260022384-A1 ASPARAGINE SYNTHETASE INHIBITORS AND USES THEREOF ASNS, AARS1, NARS1 NT5E 857/4885TGM2 533/4885IMPDH2 2637/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.