Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HPN | P05981 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15096689 | 0.79 | PNMT (0.45) | HTR2BMAOADRD2DRD4DRD3 | |
| SCHEMBL29693310 | 0.79 | PNMT (0.45) | HTR2BMAOADRD2DRD4DRD3 | |
| SCHEMBL28856359 | 0.77 | LMNA (0.44) | HTR2BPOLBDRD2DRD4DRD3 | |
| SCHEMBL30110485 | 0.77 | LMNA (0.44) | HTR2BPOLBDRD2DRD4DRD3 | |
| SCHEMBL3286498 | 0.77 | PTGS2 (0.49) | DRD2KDM4ERAB9AMAPK1ALDH1A1 | |
| SCHEMBL31290770 | 0.76 | ALDH1A1 (0.46) | MAOADRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL18350164 | 0.75 | DRD2 (0.41) | DRD2DRD4DRD3HTR2ACYP1A2 | |
| Ethylene SCHEMBL7873619 | 0.74 | PTGS2 (0.46) | DRD2KDM4ERAB9AMAPK1ALDH1A1 | |
| SCHEMBL28206950 | 0.73 | HTR2A (0.47) | HTR2BPOLBMAOADRD2KDM4E | |
| SCHEMBL28004757 | 0.72 | MAOA (0.54) | HTR2BPOLBMAOADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230292612-A1 | COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF | DUK SAN NEOLUX CO., LTD. (KR) | 2023-09-14 | — | — | US | disclosed |
| US-20230126850-A1 | HETEROCYCLIC SPIRO COMPOUNDS | MERCK PATENT GMBH (DE) | 2023-04-27 | — | — | US | disclosed |
| US-20180162843-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2018-06-14 | — | — | US | disclosed |
| US-20160308147-A1 | HETEROCYCLIC SPIRO COMPOUNDS | MERCK PATENT GMBH (DE) | 2016-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160308147-A1 | HETEROCYCLIC SPIRO COMPOUNDS | NES, KCNC1, HCN4 | HTR2B 2447/4885POLB 3232/4885MAOA 3085/4885 |
| US-20180162843-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | DDT, CELF2, BRD3 | HTR2B 2868/4885POLB 3761/4885MAOA 1116/4885 |
| US-20230292612-A1 | COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF | NFE2L2, ESR1, OR51E2 | HTR2B 4569/4885POLB 2583/4885MAOA 760/4885 |
| US-20230126850-A1 | HETEROCYCLIC SPIRO COMPOUNDS | NES, KCNC1, HCN4 | HTR2B 2447/4885POLB 3232/4885MAOA 3085/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.