Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.50 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.47 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.47 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.47 |
| ▸ | PRKCA | P17252 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18227895 | 1.00 | NR1I2 (0.52) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL29808488 | 0.87 | ADORA3 (0.68) | NR1I2PGRADORA3PTGS2PDE4D | |
| Glycerol Phenylbutyrate SCHEMBL10102804 | 0.84 | ADRB2 (0.56) | FAAHALDH1A1TDP1ADRB2ADRB1 | |
| SCHEMBL3784212 | 0.83 | ALDH1A1 (0.56) | PRKCEPRKCQPRKCDPRKCAFAAH | |
| SCHEMBL1892709 | 0.83 | ALDH1A1 (0.56) | PRKCEPRKCQPRKCDPRKCAFAAH | |
| SCHEMBL23771557 | 0.82 | PRKCA (0.65) | EPHX2PRKCEPRKCQPRKCDPRKCA | |
| SCHEMBL31210188 | 0.82 | FAAH (0.69) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL17667964 | 0.82 | ALDH1A1 (0.69) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL17133147 | 0.82 | ALDH1A1 (0.69) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL17667965 | 0.82 | ALDH1A1 (0.69) | NR1I2PGRADORA3PTGS2PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016181199-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF UREA CYCLE DISORDERS AND GOUT | MOHAN M ALAPATI (IN) | 2016-11-17 | — | — | WO | disclosed |
| US-20160332950-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF UREA CYCLE DISORDERS AND GOUT | ALAPATI MOHAN MURALI (IN) | 2016-11-17 | — | — | US | disclosed |
| US-20160332950-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF UREA CYCLE DISORDERS AND GOUT | ALAPATI MOHAN MURALI (IN) | 2016-11-17 | — | — | US | disclosed |
| US-9475747-B1 | Compositions and methods for the treatment of urea cycle disorders and gout | ALAPATI MOHAN MURALI (IN) | 2016-10-25 | — | — | US | disclosed |
| US-9475747-B1 | Compositions and methods for the treatment of urea cycle disorders and gout | ALAPATI MOHAN MURALI (IN) | 2016-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160332950-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF UREA CYCLE DISORDERS AND GOUT | SLC14A1, UMPS, UGT1A3 | NR1I2 86/4885PGR 3019/4885ADORA3 1721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.