Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18230342 | 0.85 | ADORA2A (0.44) | KDM4EMAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL18230296 | 0.84 | TRPV1 (0.54) | KDM4EMAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL18230321 | 0.82 | ADORA2A (0.48) | MAPTLMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL18230513 | 0.81 | TLR7 (0.49) | KDM4EMAPTLMNAALOX15ADORA2A | |
| SCHEMBL18230353 | 0.81 | PTGES (0.49) | KDM4EMAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL18230439 | 0.80 | LMNA (0.53) | KDM4EMAPTLMNAKMT2AL3MBTL1 | |
| SCHEMBL18230409 | 0.79 | ADORA2A (0.50) | MAPTLMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL18230361 | 0.79 | ADORA3 (0.46) | KDM4EMAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL18230503 | 0.79 | ADORA2A (0.45) | MAPTLMNASMN1; SMN2KMT2AHTT | |
| SCHEMBL18230364 | 0.78 | ADORA2A (0.42) | KDM4EMAPTSMN1; SMN2KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |