Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.47 |
| ▸ | ACP3 | P15309 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CTSG | P08311 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14376212 | 1.00 | ALDH1A1 (0.50) | ALDH1A1CYP2C9CYP2C19CYP1A2HPGD | |
| SCHEMBL4955989 | 1.00 | ALDH1A1 (0.50) | ALDH1A1CYP2C9CYP2C19CYP1A2HPGD | |
| SCHEMBL4954667 | 1.00 | ALDH1A1 (0.50) | ALDH1A1CYP2C9CYP2C19CYP1A2HPGD | |
| SCHEMBL28948611 | 0.85 | ALOX5 (0.52) | ALDH1A1CYP2C9CYP2C19HPGDHTT | |
| SCHEMBL28555282 | 0.83 | CES2 (0.53) | ALDH1A1CYP2C9CYP2C19CYP1A2HPGD | |
| SCHEMBL28564523 | 0.82 | ALDH1A1 (0.49) | ALDH1A1CYP2C9CYP2C19CYP1A2HPGD | |
| SCHEMBL4836821 | 0.82 | ALDH1A1 (0.48) | ALDH1A1CYP2C9CYP2C19CYP1A2HPGD | |
| SCHEMBL31099345 | 0.82 | ALDH1A1 (0.45) | ALDH1A1CYP2C9CYP2C19CYP1A2HPGD | |
| SCHEMBL5594564 | 0.82 | ALDH1A1 (0.45) | ALDH1A1CYP2C9CYP2C19CYP1A2HPGD | |
| SCHEMBL6051357 | 0.82 | ALDH1A1 (0.52) | ALDH1A1CYP2C9CYP2C19CYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 202 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915080-B1 | Process for preparing optically active amines and optically active carboxylic acids, and intermediates for preparation | YAMAKAWA CHEMICAL IND (JP) | 2003-03-26 | — | — | EP | claimed |
| US-6342636-B1 | REACTION OF ARYLALKYLAMINE WITH NAPHTHYLGLYCOLIC ACID AND DECOMPOSITION A DIASTEROMER SALT TO OBTAIN AN ENANTIOMORPH | YAMAKAWA CHEMICAL INDUSTRY CO., LTD. (JP) | 2002-01-29 | — | — | US | claimed |
| US-5942365-A | CHARGE ADJUVANT OF ALUMINUM SALT OF AN ACID; SMEARING, LOSS OF RESOLUTION AND LOSS OF DENSITY ELIMINATED OR MINIMIZED | XEROX CORPORATION (US) | 1999-08-24 | — | — | US | claimed |
| EP-0915080-A1 | Process for preparing optically active amines and optically active carboxylic acids, and intermediates for preparation | YAMAKAWA CHEMICAL INDUSTRY CO., LTD. (JP) | 1999-05-12 | — | — | EP | claimed |
| US-4333877-A | Substituted 2,7-dioxo-2,7-dihydrobenzo[1:2-b; 5:6-b1 ]difuran or -dipyrrole dyestuffs, their preparation and their use | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1982-06-08 | — | — | US | claimed |
| JP-11193260-A | — | — | None | — | — | JP | disclosed |
| US-12534456-B2 | Heterocyclyl pyridines as novel fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 2026-01-27 | — | — | US | disclosed |
| US-12516037-B2 | Substituted thiophenecarboxamides and analogues as antibacterials agents | BAYER AKTIENGESELLSCHAFT (DE) | 2026-01-06 | — | — | US | disclosed |
| US-20240360098-A1 | SUBSTITUTED THIOPHENECARBOXAMIDES AND ANALOGUES AS ANTIBACTERIALS AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2024-10-31 | — | — | US | disclosed |
| US-20230339934-A1 | PYRIMIDIN-4(3H)-ONE DERIVATIVES AS TRPV4 ANTAGONISTS | RAQUALIA PHARMA INC. (JP) | 2023-10-26 | — | — | US | disclosed |
| US-20230339934-A1 | PYRIMIDIN-4(3H)-ONE DERIVATIVES AS TRPV4 ANTAGONISTS | RAQUALIA PHARMA INC. (JP) | 2023-10-26 | — | — | US | disclosed |
| CN-113163750-B | Aqueous solutions of poorly soluble pesticides using polyalkoxylated alcohols | 陶氏环球技术有限责任公司 | 2023-09-29 | — | — | CN | disclosed |
| US-4207241-A | ANALGESICS, ANTIPYRETICS, ANTIINFLAMMATORY AGENTS AND ANTIPRURITIC AGENTS | SYNTEX CORPORATION (US) | 1980-06-10 | — | — | US | disclosed |
| US-4163759-A | Process for preparing aromatic hydroxyaldehydes | HAARMANN & REIMER GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-08-07 | — | — | US | disclosed |
| US-4097674-A | ANTIINFLAMMATORY, ANTIPYRETIC, ANTIPRURITIC AGENTS, ANALGESICS | SYNTEX CORPORATION (US) | 1978-06-27 | — | — | US | disclosed |
| US-4051233-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC, ANTIPRURITIC | SYNTEX CORPORATION (US) | 1977-09-27 | — | — | US | disclosed |
| US-3998966-A | Anti-inflammatory, analgesic, anti-pyretic and anti-pruritic 6-substituted 2-naphthyl acetic acid derivative-containing compositions and methods of use thereof | SYNTEX CORPORATION (PM) | 1976-12-21 | — | — | US | disclosed |
| US-3980699-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETIC, ANTIPRURITIC | SYNTEX CORPORATION (PM) | 1976-09-14 | — | — | US | disclosed |
| US-3978116-A | ANALGESIC, ANTIPYRETIC | SYNTEX CORPORATION (PM) | 1976-08-31 | — | — | US | disclosed |
| US-3978124-A | ANALGESIC, ANTIPYRETIC | SYNTEX CORPORATION (PM) | 1976-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240360098-A1 | SUBSTITUTED THIOPHENECARBOXAMIDES AND ANALOGUES AS ANTIBACTERIALS AGENTS | TST, TBK1, PGLS | ALDH1A1 4717/4885CYP2C9 2790/4885CYP2C19 3813/4885 |
| US-20230339934-A1 | PYRIMIDIN-4(3H)-ONE DERIVATIVES AS TRPV4 ANTAGONISTS | TRPV4, TRPV1, TRPV2 | ALDH1A1 1663/4885CYP2C9 2375/4885CYP2C19 1555/4885 |
| US-12534456-B2 | Heterocyclyl pyridines as novel fungicides | CBR1, CBR3, NOX1 | ALDH1A1 1511/4885CYP2C9 163/4885CYP2C19 387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.