Phthalic Acid

Phthalic Acid

SCHEMBL183234

O=C([O-])c1ccccc1C(=O)O.[K+]

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA

The experimentally established mechanism targets of Phthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.70
ALOX15 P16050 1/20 0.70
AKR1C3 P42330 3/20 0.54
KDM4E B2RXH2 2/20 0.54
HPGD P15428 2/20 0.54
CA2 P00918 2/20 0.52
CA4 P22748 2/20 0.52
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
HMGB1 P09429 1/20 0.52
CA6 P23280 1/20 0.52
CA7 P43166 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
CA9 Q16790 1/20 0.52
NAPRT Q6XQN6 1/20 0.52
CA14 Q9ULX7 1/20 0.52
MAPT P10636 1/20 0.50
HDAC8 Q9BY41 1/20 0.50
POLB P06746 1/20 0.48
CDC25B P30305 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Acid SCHEMBL28252362 1.00 ALDH1A1 (0.70) ALDH1A1ALOX15AKR1C3KDM4EHPGD
Phthalic Acid SCHEMBL27513238 1.00 ALDH1A1 (0.70) ALDH1A1ALOX15AKR1C3KDM4EHPGD
Phthalic Acid SCHEMBL8168901 1.00 ALDH1A1 (0.70) ALDH1A1ALOX15AKR1C3KDM4EHPGD
Phthalic Acid SCHEMBL588315 1.00 ALDH1A1 (0.70) ALDH1A1ALOX15AKR1C3KDM4EHPGD
Phthalic Acid SCHEMBL3914685 1.00 ALDH1A1 (0.70) ALDH1A1ALOX15AKR1C3KDM4EHPGD
Phthalic Acid SCHEMBL27618570 1.00 ALDH1A1 (0.70) ALDH1A1ALOX15AKR1C3KDM4EHPGD
Phthalic Acid SCHEMBL29397108 1.00 ALDH1A1 (0.70) ALDH1A1ALOX15AKR1C3KDM4EHPGD
Phthalic Acid SCHEMBL8730299 1.00 ALDH1A1 (0.70) ALDH1A1ALOX15AKR1C3KDM4EHPGD
Phthalic Acid SCHEMBL1930940 1.00 ALDH1A1 (0.70) ALDH1A1ALOX15AKR1C3KDM4EHPGD
Phthalic Acid SCHEMBL28014351 1.00 ALDH1A1 (0.70) ALDH1A1ALOX15AKR1C3KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 9328 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122084542-A Water quality parameter detection method based on spectrum method and chemical method mapping model 2026-05-26 CN claimed
CN-122079915-A Al (aluminum) alloy18F-labeled PSMA radioactive drug, preparation method and application thereof 2026-05-26 CN claimed
CN-122042646-A Method for detecting copper ion content in vinyl chloride 青岛海湾科技产业研究院有限公司 2026-05-15 CN claimed
EP-4739687-A1 STABLE PALIPERIDONE PALMITATE COMPOSITION USING THERMAL TREATMENT Eugia Pharma Specialities Limited (IN) 2026-05-13 EP claimed
CN-115839978-B Online analysis method for chloroprene polymerization aqueous phase liquid component concentration 山纳合成橡胶有限责任公司 2026-05-12 CN claimed
CN-122010860-A Al (aluminum) alloy18F-labeled PSMA radioactive drug, preparation method and application thereof 烟台蓝纳成生物技术股份有限公司 2026-05-12 CN claimed
EP-4715094-A1 COBALT RECOVERY METHOD Mitsubishi Materials Corporation (JP) 2026-03-25 EP claimed
US-12578341-B2 Iterative fluorescence imaging Universität Zürich (CH) 2026-03-17 US claimed
CN-121574386-A CO based on dynamic covalent bond2Responsive ionic liquid fluorescent hydrogel material and preparation method thereof 陕西科技大学 2026-02-27 CN claimed
CN-121583873-A Self-diagnosis silicon-based negative electrode plate, preparation method thereof, overvoltage judging method and application 惠州赣锋锂电科技有限公司 2026-02-27 CN claimed
US-4844898-A IODINE COMPLEX, SUGAR, BUFFER KOWA CO., LTD. (JP) 1989-07-04 US claimed
US-4828744-A ENVELOPES FOR LAUNDRY ADDITIVES THE CLOROX COMPANY (US) 1989-05-09 US claimed
US-4822743-A Method and cloth for detecting leaks in closed bodies LOCKHEED CORPORATION (US) 1989-04-18 US claimed
US-4801664-A ADJUSTED VISCOSITY, FASTER CURING PHILLIPS PETROLEUM COMPANY (US) 1989-01-31 US claimed
EP-0079712-B1 BORATE SOLUTION SOLUBLE POLYVINYL ALCOHOL FILMS The Clorox Company (US) 1988-06-08 EP claimed
US-4403039-A Method and apparatus for analysis of ionic species YOKOGAWA HOKUSHIN ELECTRIC WORKS (JP) 1983-09-06 US claimed
EP-0079712-A1 Borate solution soluble polyvinyl alcohol films The Clorox Company (US) 1983-05-25 EP claimed
US-4346709-A Drug delivery devices comprising erodible polymer and erosion rate modifier ALZA CORPORATION (US) 1982-08-31 US claimed
US-4284482-A ELECTROCHEMICAL OXIDATION BELL TELEPHONE LABORATORIES, INCORPORATED (US) 1981-08-18 US claimed
US-3934977-A COLORIMETRIC, 2,7-BIS(4-CHLORO-2-PHOSPHONOBENZENEAZO)-1,8-DIHYDROXYNAPHTHALENE-3,6 -DISULFONIC ACID AMERICAN HOSPITAL SUPPLY CORPORATION (US) 1976-01-27 US claimed