Phthalic Acid

Phthalic Acid

SCHEMBL29397108

O=C([O-])c1ccccc1C(=O)O.[K+]

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA

The experimentally established mechanism targets of Phthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.70
ALOX15 P16050 1/20 0.70
AKR1C3 P42330 3/20 0.54
KDM4E B2RXH2 2/20 0.54
HPGD P15428 2/20 0.54
CA2 P00918 2/20 0.52
CA4 P22748 2/20 0.52
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
HMGB1 P09429 1/20 0.52
CA6 P23280 1/20 0.52
CA7 P43166 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
CA9 Q16790 1/20 0.52
NAPRT Q6XQN6 1/20 0.52
CA14 Q9ULX7 1/20 0.52
MAPT P10636 1/20 0.50
HDAC8 Q9BY41 1/20 0.50
POLB P06746 1/20 0.48
CDC25B P30305 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Acid SCHEMBL28252362 1.00 ALDH1A1 (0.70) ALDH1A1ALOX15AKR1C3KDM4EHPGD
Phthalic Acid SCHEMBL183234 1.00 ALDH1A1 (0.70) ALDH1A1ALOX15AKR1C3KDM4EHPGD
Phthalic Acid SCHEMBL27513238 1.00 ALDH1A1 (0.70) ALDH1A1ALOX15AKR1C3KDM4EHPGD
Phthalic Acid SCHEMBL8168901 1.00 ALDH1A1 (0.70) ALDH1A1ALOX15AKR1C3KDM4EHPGD
Phthalic Acid SCHEMBL588315 1.00 ALDH1A1 (0.70) ALDH1A1ALOX15AKR1C3KDM4EHPGD
Phthalic Acid SCHEMBL3914685 1.00 ALDH1A1 (0.70) ALDH1A1ALOX15AKR1C3KDM4EHPGD
Phthalic Acid SCHEMBL27618570 1.00 ALDH1A1 (0.70) ALDH1A1ALOX15AKR1C3KDM4EHPGD
Phthalic Acid SCHEMBL8730299 1.00 ALDH1A1 (0.70) ALDH1A1ALOX15AKR1C3KDM4EHPGD
Phthalic Acid SCHEMBL1930940 1.00 ALDH1A1 (0.70) ALDH1A1ALOX15AKR1C3KDM4EHPGD
Phthalic Acid SCHEMBL28014351 1.00 ALDH1A1 (0.70) ALDH1A1ALOX15AKR1C3KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117924427-A Al (aluminum) alloy18F-labeled antibacterial peptide UBI 29-41 derivative and preparation method and application thereof 北京师范大学 2024-04-26 CN claimed
US-11280778-B2 Determining chemical oxygen demand SAUDI ARABIAN OIL COMPANY (SA) 2022-03-22 US claimed
CN-122084542-A Water quality parameter detection method based on spectrum method and chemical method mapping model 2026-05-26 CN disclosed
EP-3166981-B1 OLIGOSACCHARIDE COMPOSITIONS AND METHODS FOR PRODUCING THEREOF DSM NUTRITIONAL PRODUCTS LLC (US) 2026-05-13 EP disclosed
CN-122017225-A Electrochemiluminescence immunosensor for detecting interleukin-1 beta, preparation method and application thereof 杭州市第一人民医院(西湖大学附属杭州市第一人民医院) 2026-05-12 CN disclosed
WO-2026088007-A1 DISENTANGLED POLYETHYLENE AND A PROCESS TO MANUFACTURE IT BARRMAX CORP. (US) 2026-04-30 WO disclosed
US-20260083114-A1 A MODULAR AGRICULTURAL TREATMENT SYSTEM AND A METHOD FOR OPERATING A MODULAR AGRICULTURAL TREATMENT SYSTEM BASF SE (DE) 2026-03-26 US disclosed
EP-4715094-A1 COBALT RECOVERY METHOD Mitsubishi Materials Corporation (JP) 2026-03-25 EP disclosed
US-20260076294-A1 A MODULAR AGRICULTURAL TREATMENT SYSTEM AND A METHOD FOR OPERATING SAID MODULAR AGRICULTURAL TREATMENT SYSTEM BASF SE (DE) 2026-03-19 US disclosed
US-12529628-B2 Microbeads and preparation method therefor LG CHEM, LTD. (KR) 2026-01-20 US disclosed
US-12514267-B2 Oligosaccharide compositions for use as animal feed and methods of producing thereof DSM NUTRITIONAL PRODUCTS, LLC (US) 2026-01-06 US disclosed
US-20220136124-A1 Electrolyte for the Deposition of Anthracite/Black Rhodium/Ruthenium Alloy Layers UMICORE GALVANOTECHNIK GMBH (DE) 2022-05-05 US disclosed
US-11312876-B2 Ink compositions with narrow band emission phosphor materials GENERAL ELECTRIC COMPANY (US) 2022-04-26 US disclosed
US-11280778-B2 Determining chemical oxygen demand SAUDI ARABIAN OIL COMPANY (SA) 2022-03-22 US disclosed
US-11280778-B2 Determining chemical oxygen demand SAUDI ARABIAN OIL COMPANY (SA) 2022-03-22 US disclosed
US-11274329-B2 Electrochemical sensors and methods for using electrochemical sensors to detect plant pathogen infection UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2022-03-15 US disclosed
US-20220062897-A1 RAPID TESTING DEVICE FOR WASTEWATER ANALYSIS INTERNATIONAL BUSINESS MACHINES CORPORATION 2022-03-03 US disclosed
WO-2022042032-A1 RAPID TESTING DEVICE FOR WASTEWATER ANALYSIS INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2022-03-03 WO disclosed
CN-114075268-A Affinity body targeting HER2 and application thereof 北京肿瘤医院(北京大学肿瘤医院) 2022-02-22 CN disclosed
US-11254864-B2 Films with narrow band emission phosphor materials GENERAL ELECTRIC COMPANY (US) 2022-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260083114-A1 A MODULAR AGRICULTURAL TREATMENT SYSTEM AND A METHOD FOR OPERATING A MODULAR AGRICULTURAL TREATMENT SYSTEM FAH, FAHD1, BROX ALDH1A1 2837/4885ALOX15 2624/4885AKR1C3 735/4885
US-20260076294-A1 A MODULAR AGRICULTURAL TREATMENT SYSTEM AND A METHOD FOR OPERATING SAID MODULAR AGRICULTURAL TREATMENT SYSTEM BCHE, ACHE, ALPG ALDH1A1 4479/4885ALOX15 3284/4885AKR1C3 1742/4885
US-12529628-B2 Microbeads and preparation method therefor SLC6A11, SLC16A7, SLC5A11 ALDH1A1 1940/4885ALOX15 4334/4885AKR1C3 1478/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.