Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Phthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.70 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA4 | P22748 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CDC25B | P30305 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Acid SCHEMBL28252362 | 1.00 | ALDH1A1 (0.70) | ALDH1A1ALOX15AKR1C3KDM4EHPGD | |
| Phthalic Acid SCHEMBL183234 | 1.00 | ALDH1A1 (0.70) | ALDH1A1ALOX15AKR1C3KDM4EHPGD | |
| Phthalic Acid SCHEMBL27513238 | 1.00 | ALDH1A1 (0.70) | ALDH1A1ALOX15AKR1C3KDM4EHPGD | |
| Phthalic Acid SCHEMBL8168901 | 1.00 | ALDH1A1 (0.70) | ALDH1A1ALOX15AKR1C3KDM4EHPGD | |
| Phthalic Acid SCHEMBL3914685 | 1.00 | ALDH1A1 (0.70) | ALDH1A1ALOX15AKR1C3KDM4EHPGD | |
| Phthalic Acid SCHEMBL27618570 | 1.00 | ALDH1A1 (0.70) | ALDH1A1ALOX15AKR1C3KDM4EHPGD | |
| Phthalic Acid SCHEMBL29397108 | 1.00 | ALDH1A1 (0.70) | ALDH1A1ALOX15AKR1C3KDM4EHPGD | |
| Phthalic Acid SCHEMBL8730299 | 1.00 | ALDH1A1 (0.70) | ALDH1A1ALOX15AKR1C3KDM4EHPGD | |
| Phthalic Acid SCHEMBL1930940 | 1.00 | ALDH1A1 (0.70) | ALDH1A1ALOX15AKR1C3KDM4EHPGD | |
| Phthalic Acid SCHEMBL28014351 | 1.00 | ALDH1A1 (0.70) | ALDH1A1ALOX15AKR1C3KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12529628-B2 | Microbeads and preparation method therefor | LG CHEM, LTD. (KR) | 2026-01-20 | — | — | US | claimed |
| CN-116516433-B | Green rapid preparation method of metal organic framework compound film coating | 中国科学院深圳先进技术研究院 | 2024-04-26 | — | — | CN | claimed |
| CN-116516433-A | Green rapid preparation method of metal organic framework compound film coating | 中国科学院深圳先进技术研究院 | 2023-08-01 | — | — | CN | claimed |
| WO-2023138283-A1 | ENVIRONMENTALLY FRIENDLY AND RAPID PREPARATION METHOD FOR METAL-ORGANIC FRAMEWORK COMPOUND THIN FILM PLATING | 中国科学院深圳先进技术研究院 | 2023-07-27 | — | — | WO | claimed |
| US-11472927-B2 | Polyphosphazenes, methods of making, and uses thereof | UNIVERSITY OF MARYLAND, COLLEGE PARK (US) | 2022-10-18 | — | — | US | claimed |
| US-20180327550-A1 | POLYPHOSPHAZENES, METHODS OF MAKING, AND USES THEREOF | UNIVERSITY OF MARYLAND, COLLEGE PARK | 2018-11-15 | — | — | US | claimed |
| EP-3377560-A1 | POLYPHOSPHAZENES, METHODS OF MAKING, AND USES THEREOF | University of Maryland, College Park (US) | 2018-09-26 | — | — | EP | claimed |
| US-20130184499-A1 | PREPARATION OF CATALYST FOR SELECTIVE HYDROGENATION OF HYDROGENATABLE PRECURSORS | BIOAMBER INTERNATIONAL S.A.R.L. (LU) | 2013-07-18 | — | — | US | claimed |
| WO-2013106519-A1 | PREPARATION OF CATALYST FOR SELECTIVE HYDROGENATION OF HYDROGENATABLE PRECURSORS | BIOAMBER INTERNATIONAL S.A.R.L. (LU) | 2013-07-18 | — | — | WO | claimed |
| US-20260077088-A1 | SELF-DEGRADING ENZYME LOADED BIOLOGICALLY DERIVED PARTICLES | CRANNMED LIMITED (IE) | 2026-03-19 | — | — | US | disclosed |
| US-20260053152-A1 | COMPOSITIONS AND METHODS OF TREATING EDIBLE MATTER AND SUBSTRATES THEREFOR | SAVE FOODS LTD. (IL) | 2026-02-26 | — | — | US | disclosed |
| US-12527331-B2 | Compositions and methods of treating edible matter and substrates therefor | SAVE FOODS LTD. (IL) | 2026-01-20 | — | — | US | disclosed |
| US-12529628-B2 | Microbeads and preparation method therefor | LG CHEM, LTD. (KR) | 2026-01-20 | — | — | US | disclosed |
| US-12465600-B2 | Pediatric suspension formulation | Xeolas Pharmaceuticals Ltd. (IE) | 2025-11-11 | — | — | US | disclosed |
| US-20090023766-A1 | Pharmaceutical formulation of apomorphine for buccal administration | AMARIN PHARMACEUTICALS IRELAND LIMITED (IE) | 2009-01-22 | — | — | US | disclosed |
| CN-101217936-A | Pharmaceutical formulations of apomorphine for oral administration | AMARIN PHARMACEUTICALS IRELAND (IE) | 2008-07-09 | — | — | CN | disclosed |
| EP-1885333-A1 | PHARMACEUTICAL FORMULATION OF APOMORPHINE FOR BUCCAL ADMINISTRATION | Amarin Pharmaceuticals Ireland Limited (IE) | 2008-02-13 | — | — | EP | disclosed |
| WO-2006120412-A1 | PHARMACEUTICAL FORMULATION OF APOMORPHINE FOR BUCCAL ADMINISTRATION | AMARIN PHARMACEUTICALS IRELAND LIMITED (IE) | 2006-11-16 | — | — | WO | disclosed |
| US-20050227225-A1 | Stabilization of biomolecules in samples | ROCHE MOLECULAR SYSTEMS, INC. (US) | 2005-10-13 | — | — | US | disclosed |
| EP-1584923-A2 | Stabilization of biomolecules in samples | Roche Diagnostics GmbH (DE) | 2005-10-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180327550-A1 | POLYPHOSPHAZENES, METHODS OF MAKING, AND USES THEREOF | PHOSPHO1, PLCG2, PLCG1 | ALDH1A1 4658/4885ALOX15 1056/4885AKR1C3 4820/4885 |
| US-11472927-B2 | Polyphosphazenes, methods of making, and uses thereof | PHOSPHO1, PLCG2, PLCG1 | ALDH1A1 4658/4885ALOX15 1056/4885AKR1C3 4820/4885 |
| US-20260053152-A1 | COMPOSITIONS AND METHODS OF TREATING EDIBLE MATTER AND SUBSTRATES THEREFOR | SOAT2, AGL, SOAT1 | ALDH1A1 3116/4885ALOX15 1442/4885AKR1C3 745/4885 |
| US-12527331-B2 | Compositions and methods of treating edible matter and substrates therefor | AGL, SOAT2, SOAT1 | ALDH1A1 3249/4885ALOX15 1256/4885AKR1C3 813/4885 |
| US-20090023766-A1 | Pharmaceutical formulation of apomorphine for buccal administration | PARK7, SNCA, AMY2A | ALDH1A1 1946/4885ALOX15 644/4885AKR1C3 671/4885 |
| US-20260077088-A1 | SELF-DEGRADING ENZYME LOADED BIOLOGICALLY DERIVED PARTICLES | MMP2, PLG, PMM2 | ALDH1A1 442/4885ALOX15 3668/4885AKR1C3 3874/4885 |
| US-12529628-B2 | Microbeads and preparation method therefor | SLC6A11, SLC16A7, SLC5A11 | ALDH1A1 1940/4885ALOX15 4334/4885AKR1C3 1478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.