SCHEMBL18339142

SCHEMBL18339142

CC(C)[C@H](NC(=O)[C@@H](N)CCC(=O)O)C(=O)NCC(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.55
DPP8 Q6V1X1 2/20 0.55
DPP9 Q86TI2 2/20 0.55
PTGS1 P23219 1/20 0.45
GSTK1 Q9Y2Q3 1/20 0.45
BACE1 P56817 5/20 0.44
CTSD P07339 2/20 0.44
GLO1 Q04760 1/20 0.42
LMNA P02545 2/20 0.42
ALDH1A1 P00352 1/20 0.42
MAPT P10636 1/20 0.42
PTGS2 P35354 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
GABRP O00591 2/20 0.42
GABRD O14764 2/20 0.42
GABRA1 P14867 2/20 0.42
GABRB1 P18505 2/20 0.42
GABRG2 P18507 2/20 0.42
GABRB3 P28472 2/20 0.42
GABRA5 P31644 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20542530 1.00 DPP4 (0.55) DPP4DPP8DPP9PTGS1GSTK1
SCHEMBL18339144 0.91 DPP4 (0.52) DPP4DPP8DPP9PTGS1GSTK1
SCHEMBL29538909 0.90 DPP4 (0.54) DPP4DPP8DPP9PTGS1GSTK1
SCHEMBL29870202 0.89 BACE1 (0.49) DPP4DPP8DPP9PTGS1GSTK1
SCHEMBL24591966 0.84 DPP4 (0.58) DPP4DPP8DPP9BACE1CTSD
SCHEMBL29531781 0.84 DPP4 (0.58) DPP4DPP8DPP9BACE1CTSD
SCHEMBL14359921 0.84 DPP4 (0.58) DPP4DPP8DPP9PTGS1GSTK1
SCHEMBL30052468 0.84 FNTA (0.43) DPP4DPP8DPP9PTGS1GSTK1
SCHEMBL537127 0.84 DPP4 (0.61) DPP4DPP8DPP9BACE1CTSD
SCHEMBL537129 0.84 DPP4 (0.61) DPP4DPP8DPP9BACE1CTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250302080-A1 SWEETNESS AND/OR FLAVOR ENHANCER AJINOMOTO CO., INC. (JP) 2025-10-02 US claimed
EP-4613108-A1 SWEETNESS AND/OR FLAVOR ENHANCER AJINOMOTO CO., INC. (JP) 2025-09-10 EP claimed
CN-120152627-A Sweetness and/or flavor enhancer 味之素株式会社 2025-06-13 CN claimed
CN-118897023-B Method for directly measuring alpha and gamma-glutamyl peptide in skeletal muscle by using LC-MS and isotope dilution assay 中国农业科学院北京畜牧兽医研究所 2025-03-25 CN claimed
EP-4507522-A1 TASTE MODIFYING COMPOSITIONS AND USES THEREOF Firmenich SA (CH) 2025-02-19 EP claimed
CN-118897023-A Method for directly measuring alpha and gamma-glutamyl peptide in skeletal muscle by using LC-MS and isotope dilution assay 中国农业科学院北京畜牧兽医研究所 2024-11-05 CN claimed
WO-2024096132-A1 SWEETNESS AND/OR FLAVOR ENHANCER 味の素株式会社 2024-05-10 WO claimed
US-20240036041-A1 KOKUMI TASTE ENHANCEMENT AND RELATED SCREENING METHODS FIRMENICH INCORPORATED (US) 2024-02-01 US claimed
WO-2023247332-A1 TASTE MODIFYING COMPOSITIONS AND USES THEREOF FIRMENICH SA (CH) 2023-12-28 WO claimed
EP-4211469-A1 KOKUMI TASTE ENHANCEMENT AND RELATED SCREENING METHODS Firmenich Incorporated (US) 2023-07-19 EP claimed
EP-3538543-B1 PROTRANSDUZIN-S - AN ENHANCER OF GENE TRANSFER PHARIS BIOTEC GMBH (DE) 2022-06-08 EP claimed
WO-2022115837-A1 KOKUMI TASTE ENHANCEMENT AND RELATED SCREENING METHODS FIRMENICH INCORPORATED (US) 2022-06-02 WO claimed
WO-2026070371-A1 ENZYMATIC REACTION COMPOSITION OF COFFEE BEANS OR COFFEE GROUNDS, FERMENTATION COMPOSITION OF COFFEE BEANS OR COFFEE GROUNDS, METHODS FOR PRODUCING SAME, AND SEASONING COMPOSITION 株式会社ファーメンステーション 2026-04-02 WO disclosed
US-20260091067-A1 METHODS AND USES OF MICROBIOME COMPOSITIONS, COMPONENTS, OR METABOLITES FOR TREATING INSULIN-ASSOCIATED DISEASES MARVELBIOME INC (US) 2026-04-02 US disclosed
EP-4679087-A1 BIOMARKER AND USE THEREOF MEIJI CO., LTD (JP) 2026-01-14 EP disclosed
EP-4666864-A1 METHOD FOR PRODUCING MODIFIED PROTEIN-CONTAINING FOOD AJINOMOTO CO., INC. (JP) 2025-12-24 EP disclosed
US-20170119032-A1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED 2017-05-04 US disclosed
US-20170096418-A1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 FIRMENICH INCORPORATED 2017-04-06 US disclosed
US-20170087199-A1 COMPOSITIONS FOR DELIVERING A COOLING SENSATION SENOMYX INC (US) 2017-03-30 US disclosed
US-20160376263-A1 BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF SENOMYX INC (US) 2016-12-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170119032-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 DPP4 743/4885DPP8 1035/4885DPP9 924/4885
US-20160376263-A1 BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF TAS2R5, TAS1R1, TAS2R1 DPP4 2533/4885DPP8 2465/4885DPP9 2106/4885
US-20260091067-A1 METHODS AND USES OF MICROBIOME COMPOSITIONS, COMPONENTS, OR METABOLITES FOR TREATING INSULIN-ASSOCIATED DISEASES IAPP, GPR119, FAHD1 DPP4 1133/4885DPP8 2274/4885DPP9 2058/4885
US-20170087199-A1 COMPOSITIONS FOR DELIVERING A COOLING SENSATION TRPA1, PDE6G, PDE6D DPP4 1291/4885DPP8 1545/4885DPP9 897/4885
US-20170096418-A1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 TRPM8, TRPM6, TRPM4 DPP4 3386/4885DPP8 322/4885DPP9 2861/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.