Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGAV | P06756 | 1/20 | 0.32 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30477497 | 1.00 | POLB (0.37) | POLBSLC6A4SLC6A3CRHBPCRHR2 | |
| SCHEMBL9461467 | 0.81 | POLB (0.39) | POLBSLC6A4SLC6A3TSHRKMT2A | |
| SCHEMBL28536408 | 0.79 | POLB (0.39) | POLBSLC6A4SLC6A3CRHBPCRHR2 | |
| SCHEMBL27777776 | 0.75 | POLB (0.53) | POLBSLC6A4SLC6A3TSHRKMT2A | |
| SCHEMBL21925569 | 0.73 | LMNA (0.36) | POLBTSHRKMT2AHDAC3HDAC4 | |
| SCHEMBL20026779 | 0.72 | KMT2A (0.41) | TSHRKMT2AALDH1A1 | |
| SCHEMBL434649 | 0.72 | POLB (0.52) | POLBSLC6A4SLC6A3TSHRKMT2A | |
| SCHEMBL18947918 | 0.72 | BRD4 (0.30) | BRD4 | |
| SCHEMBL472820 | 0.70 | TSHR (0.41) | POLBTSHRKMT2ACACNA1G | |
| SCHEMBL28468467 | 0.70 | TSHR (0.38) | POLBSLC6A4SLC6A3TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3508476-B1 | AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION | SHANGHAI KECHOW PHARMA INC (CN) | 2023-11-22 | — | — | EP | disclosed |
| CN-114163354-B | Preparation method of N-fluorenylmethoxycarbonyl-N-trityl-L-asparagine | 常州吉恩药业有限公司 | 2023-05-05 | — | — | CN | disclosed |
| EP-3640242-B1 | ROCK-INHIBITING COMPOUND AND USES THEREOF | HITGEN LTD (CN) | 2023-04-19 | — | — | EP | disclosed |
| US-11078161-B2 | Rock-inhibiting compound and uses thereof | HITGEN INC. (CN) | 2021-08-03 | — | — | US | disclosed |
| US-11008286-B2 | Amino mercaptan compound and preparation method therefor and use thereof in protection against radiation | SHANGHAI KECHOW PHARMA, INC (CN) | 2021-05-18 | — | — | US | disclosed |
| CN-109134367-B | Compound for inhibiting ROCK and application thereof | 成都先导药物开发股份有限公司 | 2020-10-02 | — | — | CN | disclosed |
| US-20200190035-A1 | ROCK-INHIBITING COMPOUND AND USES THEREOF | HITGEN INC. (CN) | 2020-06-18 | — | — | US | disclosed |
| EP-3640242-A1 | ROCK-INHIBITING COMPOUND AND USES THEREOF | Hitgen Ltd. (CN) | 2020-04-22 | — | — | EP | disclosed |
| EP-3508476-A1 | AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION | Inst Of Radiation Medicine Chinese Acad Of Medical Sciences (CN) | 2019-07-10 | — | — | EP | disclosed |
| US-20190202779-A1 | AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION | SHANGHAI KECHOW PHARMA, INC. (CN) | 2019-07-04 | — | — | US | disclosed |
| US-20060228784-A1 | Sugar chain asparagine derivatives, sugar chain asparagine, sugar chain, and processes for producing these | GLYTECH, INC (JP) | 2006-10-12 | — | — | US | disclosed |
| US-20060166929-A1 | Sugar-chain asparagine derivatives and processes for the preparation thereof | OTSUKA CHEMICAL CO., LTD. (JP) | 2006-07-27 | — | — | US | disclosed |
| CN-1809590-A | Mediators of reverse cholesterol transport for the treatment of hypercholesterolemia | AVANIR PHARMACEUTICALS (US) | 2006-07-26 | — | — | CN | disclosed |
| EP-1577397-A1 | SUGAR CHAIN ASPARAGINE DERIVATIVES, SUGAR CHAIN ASPARAGINE, SUGAR CHAIN, AND PROCESSES FOR PRODUCING THESE | Kajihara, Yasuhiro (JP) | 2005-09-21 | — | — | EP | disclosed |
| EP-1577316-A1 | SUGAR-CHAIN ASPARAGINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Kajihara, Yasuhiro (JP) | 2005-09-21 | — | — | EP | disclosed |
| US-20040181054-A1 | Process for producing sugar chain asparagine derivative | GLYTECH, INC. (JP) | 2004-09-16 | — | — | US | disclosed |
| EP-1405858-A1 | PROCESS FOR PRODUCING SUGAR CHAIN ASPARAGINE DERIVATIVE | Otsuka Chemical Holdings Co., Ltd. (JP) | 2004-04-07 | — | — | EP | disclosed |
| EP-0808829-B1 | Fluorescent group-containing carbodiimide compound | NISSHIN SPINNING (JP) | 2003-04-09 | — | — | EP | disclosed |
| US-5856479-A | LABEL FOR NUCLEIC ACID DETECTION, IMMUNOASSAY OR CHEMILUMINESCENCE | NISSHINBO INDUSTRIES, INC. (JP) | 1999-01-05 | — | — | US | disclosed |
| EP-0808829-A1 | Fluorescent group-containing carbodiimide compound | NISSHINBO INDUSTRIES, INC. (JP) | 1997-11-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060228784-A1 | Sugar chain asparagine derivatives, sugar chain asparagine, sugar chain, and processes for producing these | FUT6, B3GNT2, FUT5 | POLB 3145/4885SLC6A4 687/4885SLC6A3 711/4885 |
| US-20190202779-A1 | AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION | MGMT, PRMT8, SULT1A1 | POLB 4038/4885SLC6A4 1311/4885SLC6A3 1290/4885 |
| US-11078161-B2 | Rock-inhibiting compound and uses thereof | ROCK1, ROCK2, RHOA | POLB 4662/4885SLC6A4 4162/4885SLC6A3 3375/4885 |
| US-20060166929-A1 | Sugar-chain asparagine derivatives and processes for the preparation thereof | ASNS, B3GNT2, FUT6 | POLB 2850/4885SLC6A4 573/4885SLC6A3 737/4885 |
| US-20200190035-A1 | ROCK-INHIBITING COMPOUND AND USES THEREOF | ROCK1, ROCK2, RHOA | POLB 4662/4885SLC6A4 4162/4885SLC6A3 3375/4885 |
| US-11008286-B2 | Amino mercaptan compound and preparation method therefor and use thereof in protection against radiation | MGMT, GSTA1, PRMT1 | POLB 3798/4885SLC6A4 2162/4885SLC6A3 2618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.