Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.37 |
| ▸ | KRAS | P01116 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18357443 | 0.85 | HPGD (0.41) | KDM4EALDH1A1HSD17B10HPGDHTT | |
| SCHEMBL18357573 | 0.71 | LMNA (0.43) | KDM4EALDH1A1HSD17B10HPGDMEN1 | |
| SCHEMBL2033730 | 0.70 | PTGDR2 (0.40) | ALDH1A1MEN1KMT2ALMNAPLA2G2A | |
| SCHEMBL21462437 | 0.70 | L3MBTL1 (0.45) | KDM4EALDH1A1HSD17B10HPGDHTT | |
| SCHEMBL23903663 | 0.70 | PKMYT1 (0.58) | ALDH1A1HSD17B10HPGDHTTMEN1 | |
| SCHEMBL9261071 | 0.69 | ALDH1A1 (0.54) | KDM4EALDH1A1HSD17B10HPGDHTT | |
| SCHEMBL2321756 | 0.69 | L3MBTL1 (0.44) | KDM4EALDH1A1HSD17B10HPGDHTT | |
| SCHEMBL31368105 | 0.67 | NR4A2 (0.37) | KDM4EALDH1A1HPGDHTTKMT2A | |
| SCHEMBL4160132 | 0.66 | OPRK1 (0.44) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL2041118 | 0.66 | PTGDR2 (0.47) | KDM4EALDH1A1HSD17B10HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10364232-B2 | Antibacterial compounds | JANSSEN SCIENCES IRELAND UC (IE) | 2019-07-30 | — | — | US | disclosed |
| US-20180186768-A1 | Antibacterial Compounds | JANSSEN SCIENCES IRELAND UC (IE) | 2018-07-05 | — | — | US | disclosed |
| US-20180186768-A1 | Antibacterial Compounds | JANSSEN SCIENCES IRELAND UC (IE) | 2018-07-05 | — | — | US | disclosed |
| US-20180155341-A1 | Antibacterial Compounds | JANSSEN SCIENCES IRELAND UC (IE) | 2018-06-07 | — | — | US | disclosed |
| US-20180155341-A1 | Antibacterial Compounds | JANSSEN SCIENCES IRELAND UC (IE) | 2018-06-07 | — | — | US | disclosed |
| WO-2017001660-A1 | ANTIBACTERIAL COMPOUNDS | JANSSEN SCIENCES IRELAND UC (IE) | 2017-01-05 | — | — | WO | disclosed |
| WO-2017001661-A1 | ANTIBACTERIAL COMPOUNDS | JANSSEN SCIENCES IRELAND UC (IE) | 2017-01-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10364232-B2 | Antibacterial compounds | FDPS, SQOR, NDUFS3 | KDM4E 3387/4885ALDH1A1 1869/4885HSD17B10 1973/4885 |
| US-20180186768-A1 | Antibacterial Compounds | FDPS, SQOR, NDUFS3 | KDM4E 3387/4885ALDH1A1 1869/4885HSD17B10 1973/4885 |
| US-20180155341-A1 | Antibacterial Compounds | FDPS, SQOR, NDUFS3 | KDM4E 3387/4885ALDH1A1 1869/4885HSD17B10 1973/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.