SCHEMBL1836465

SCHEMBL1836465

Ic1ccc(-c2nnc(-c3ccccc3)o2)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 15/20 0.74
RAB9A P51151 15/20 0.74
SMN1; SMN2 Q16637 9/20 0.74
HPGD P15428 7/20 0.64
NFKB1 P19838 2/20 0.64
NFKB2 Q00653 2/20 0.64
RELA Q04206 2/20 0.64
POLB P06746 1/20 0.64
MEN1 O00255 1/20 0.64
KMT2A Q03164 1/20 0.64
ALDH1A1 P00352 5/20 0.62
KDM4E B2RXH2 4/20 0.62
HSD17B10 Q99714 2/20 0.62
GLA P06280 1/20 0.62
MAPT P10636 1/20 0.62
ALOX15 P16050 1/20 0.62
APP P05067 1/20 0.61
ATAD2 Q6PL18 1/20 0.61
NOTUM Q6P988 1/20 0.55
CA1 P00915 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2382016 0.91 APP (0.70) NPC1RAB9ASMN1; SMN2HPGDNFKB1
SCHEMBL4343181 0.89 NPC1 (0.94) NPC1RAB9ASMN1; SMN2HPGDNFKB1
SCHEMBL74999 0.86 NPC1 (0.90) NPC1RAB9ASMN1; SMN2HPGDNFKB1
SCHEMBL22858502 0.86 NPC1 (0.90) NPC1RAB9ASMN1; SMN2HPGDNFKB1
SCHEMBL46424 0.86 NPC1 (0.90) NPC1RAB9ASMN1; SMN2HPGDNFKB1
SCHEMBL522555 0.86 NPC1 (0.90) NPC1RAB9ASMN1; SMN2HPGDNFKB1
SCHEMBL46426 0.86 NPC1 (1.00) NPC1RAB9ASMN1; SMN2HPGDNFKB1
SCHEMBL1105099 0.84 NPC1 (0.85) NPC1RAB9ASMN1; SMN2HPGDNFKB1
SCHEMBL17614675 0.82 NPC1 (0.81) NPC1RAB9ASMN1; SMN2HPGDNFKB1
SCHEMBL13178438 0.82 NPC1 (0.73) NPC1RAB9ASMN1; SMN2HPGDNFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119431157-A Fluorene derivative, light-emitting element, light-emitting device, electronic device, and lighting device 株式会社半导体能源研究所 2025-02-14 CN disclosed
CN-113698305-A Fluorene derivative, light-emitting element, light-emitting device, electronic device, and lighting device 株式会社半导体能源研究所 2021-11-26 CN disclosed
US-10862042-B2 Fluorene derivative, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2020-12-08 US disclosed
US-10862042-B2 Fluorene derivative, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2020-12-08 US disclosed
US-20200119276-A1 FLUORENE DERIVATIVE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2020-04-16 US disclosed
US-20200119276-A1 FLUORENE DERIVATIVE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2020-04-16 US disclosed
US-10553797-B2 Fluorene derivative, light-emitting elements, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2020-02-04 US disclosed
US-10553797-B2 Fluorene derivative, light-emitting elements, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2020-02-04 US disclosed
US-10243151-B2 Organic semiconductor material and light-emitting element, light-emitting device, lighting system, and electronic device using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-03-26 US disclosed
US-10243151-B2 Organic semiconductor material and light-emitting element, light-emitting device, lighting system, and electronic device using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-03-26 US disclosed
WO-2010027004-A1 ORGANIC SEMICONDUCTOR MATERIAL AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, LIGHTING SYSTEM, AND ELECTRONIC DEVICE USING THE SAME SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-03-11 WO disclosed
WO-2010027004-A1 ORGANIC SEMICONDUCTOR MATERIAL AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, LIGHTING SYSTEM, AND ELECTRONIC DEVICE USING THE SAME SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-03-11 WO disclosed
WO-2010026859-A1 LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-03-11 WO disclosed
US-20100059741-A1 Light-Emitting Element, Light-Emitting Device, and Electronic Device Semiconductor Energy Laboratorry Co, Ltd. 2010-03-11 US disclosed
US-20100059741-A1 Light-Emitting Element, Light-Emitting Device, and Electronic Device Semiconductor Energy Laboratorry Co, Ltd. 2010-03-11 US disclosed
US-20100059741-A1 Light-Emitting Element, Light-Emitting Device, and Electronic Device Semiconductor Energy Laboratorry Co, Ltd. 2010-03-11 US disclosed
WO-2010026859-A1 LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-03-11 WO disclosed
US-20100060155-A1 Organic Semiconductor Material and Light-Emitting Element, Light-Emitting Device, Lighting System, and Electronic Device Using the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-03-11 US disclosed
US-20100060155-A1 Organic Semiconductor Material and Light-Emitting Element, Light-Emitting Device, Lighting System, and Electronic Device Using the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-03-11 US disclosed
US-20100060155-A1 Organic Semiconductor Material and Light-Emitting Element, Light-Emitting Device, Lighting System, and Electronic Device Using the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-03-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10243151-B2 Organic semiconductor material and light-emitting element, light-emitting device, lighting system, and electronic device using the same OXA1L, BECN1, MAP1LC3A NPC1 4299/4885RAB9A 3158/4885SMN1; SMN2 3015/4885
US-20100060155-A1 Organic Semiconductor Material and Light-Emitting Element, Light-Emitting Device, Lighting System, and Electronic Device Using the Same OXA1L, BECN1, MAP1LC3A NPC1 4299/4885RAB9A 3158/4885SMN1; SMN2 3015/4885
US-20200119276-A1 FLUORENE DERIVATIVE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE NR2E3, AFF1, NR2E1 NPC1 2194/4885RAB9A 541/4885SMN1; SMN2 2606/4885
US-10862042-B2 Fluorene derivative, light-emitting element, light-emitting device, electronic device, and lighting device NR2E3, AFF1, NR2E1 NPC1 2194/4885RAB9A 541/4885SMN1; SMN2 2606/4885
US-10553797-B2 Fluorene derivative, light-emitting elements, light-emitting device, electronic device, and lighting device NR2E3, GRK1, AFF1 NPC1 2189/4885RAB9A 509/4885SMN1; SMN2 2515/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.