Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 2/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | SCD5 | Q86SK9 | 4/20 | 0.41 |
| ▸ | CCNC | P24863 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
| ▸ | SCD | O00767 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17151081 | 0.83 | LMNA (0.46) | PROKR1GRM5RIPK1MAPT | |
| SCHEMBL2961636 | 0.80 | SCD5 (0.42) | RIPK1USP30SCD5ROCK2SCD | |
| SCHEMBL22473361 | 0.80 | PRMT5 (0.43) | RIPK1PRMT5WDR77MAPT | |
| SCHEMBL17142344 | 0.78 | CXCR4 (0.44) | GRM5RIPK1SCD5PRMT5WDR77 | |
| SCHEMBL17142323 | 0.76 | RIPK1 (0.55) | RIPK1SCD5CCNCCDK8PRMT5 | |
| SCHEMBL7520129 | 0.75 | PRMT5 (0.53) | RIPK1SCD5PRMT5WDR77SCD | |
| SCHEMBL17558248 | 0.74 | RIPK1 (0.69) | RIPK1SCD5CCNCCDK8SCD | |
| SCHEMBL1853141 | 0.74 | RIPK1 (0.69) | RIPK1SCD5CCNCCDK8SCD | |
| SCHEMBL1847627 | 0.74 | RIPK1 (0.69) | RIPK1SCD5CCNCCDK8SCD | |
| SCHEMBL27341297 | 0.73 | PRMT5 (0.49) | GRM5RIPK1SCD5PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170022185-A1 | DECARBOXYLATIVE CROSS-COUPLING AND APPLICATIONS THEREOF | THE TRUSTEES OF PRINCETON UNIVERSITY | 2017-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170022185-A1 | DECARBOXYLATIVE CROSS-COUPLING AND APPLICATIONS THEREOF | PPOX, DDO, DDC | PROKR1 4721/4885GRM5 1483/4885RIPK1 3255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.