Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.34 |
| ▸ | ITGB3 known ✓ | P05106 | 1/20 | 0.33 |
| ▸ | HDAC3 known ✓ | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 known ✓ | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 known ✓ | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 known ✓ | Q9BY41 | 1/20 | 0.31 |
| ▸ | ECE1 | P42892 | 4/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL3737520 | 1.00 | ECE1 (0.41) | ECE1PLA2G2AFAAHCNR1CNR2 | |
| Water SCHEMBL1839784 | 1.00 | ECE1 (0.41) | ECE1PLA2G2AFAAHCNR1CNR2 | |
| Water SCHEMBL19970536 | 1.00 | ECE1 (0.41) | ECE1PLA2G2AFAAHCNR1CNR2 | |
| SCHEMBL830627 | 0.98 | ECE1 (0.42) | ECE1PLA2G2AFAAHCNR1CNR2 | |
| SCHEMBL177727 | 0.98 | ECE1 (0.42) | ECE1PLA2G2AFAAHCNR1CNR2 | |
| Hydrochloric Acid SCHEMBL957867 | 0.96 | ECE1 (0.41) | ECE1PLA2G2AFAAHCNR1CNR2 | |
| Hydrochloric Acid SCHEMBL4797820 | 0.96 | ECE1 (0.41) | ECE1PLA2G2AFAAHCNR1CNR2 | |
| Water SCHEMBL158122 | 0.81 | ECE1 (0.39) | ECE1PLA2G2AFAAHCNR1CNR2 | |
| Water SCHEMBL502962 | 0.81 | ECE1 (0.39) | ECE1PLA2G2AFAAHCNR1CNR2 | |
| Water SCHEMBL27080 | 0.81 | ECE1 (0.39) | ECE1PLA2G2AFAAHCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110950989-B | Method for producing monodisperse particles | N科研中心私人投资有限公司 | 2023-01-10 | — | — | CN | claimed |
| US-9821060-B2 | Heat-sensitive nanoparticle system | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2017-11-21 | — | — | US | claimed |
| EP-2948180-B1 | HEAT-SENSITIVE NANOPARTICLE SYSTEM | FOND ST ITALIANO TECNOLOGIA (IT) | 2017-05-10 | — | — | EP | claimed |
| US-20150359887-A1 | Heat-Sensitive Nanoparticle System | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2015-12-17 | — | — | US | claimed |
| US-20250250468-A1 | PRESSURE-SENSITIVE ADHESIVE ARTICLE | NITTO DENKO CORPORATION (JP) | 2025-08-07 | — | — | US | disclosed |
| CN-119895609-A | Polymer electrolyte containing polyacrylamide and method for producing same | 尤米科尔公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-119866562-A | Polymer electrolyte containing polyacrylamide and method for producing same | 尤米科尔公司 | 2025-04-22 | — | — | CN | disclosed |
| CN-119816951-A | Composite cathode comprising a polymer electrolyte and a nickel-based cathode active material | 尤米科尔公司 | 2025-04-11 | — | — | CN | disclosed |
| CN-119816975-A | Electrochemical cell comprising a polymer electrolyte and a nickel-based cathode active material | 尤米科尔公司 | 2025-04-11 | — | — | CN | disclosed |
| CN-119816976-A | Electrochemical cell comprising a polymer electrolyte and a nickel-based cathode active material | 尤米科尔公司 | 2025-04-11 | — | — | CN | disclosed |
| CN-110950989-B | Method for producing monodisperse particles | N科研中心私人投资有限公司 | 2023-01-10 | — | — | CN | disclosed |
| US-10423023-B2 | Method for preparing liquid crystal capsule | LG CHEM, LTD. (KR) | 2019-09-24 | — | — | US | disclosed |
| EP-1703327-B1 | Composition for forming antireflection film, laminate, and method for forming resist pattern | JSR CORP (JP) | 2011-05-11 | — | — | EP | disclosed |
| EP-2241911-A1 | METHOD FOR PEELING ADHESIVE OPTICAL FILM, AND ADHESIVE OPTICAL FILM | Nitto Denko Corporation (JP) | 2010-10-20 | — | — | EP | disclosed |
| US-20100112475-A1 | RESIN FOR FORMATION OF UPPER ANTIREFLECTIVE FILM, COMPOSITION FOR FORMATION OF UPPER ANTIREFLECTIVE FILM, AND RESIST PATTERN FORMATION METHOD | JSR CORPORATION (JP) | 2010-05-06 | — | — | US | disclosed |
| US-7514205-B2 | Composition for forming antireflection film, laminate, and method for forming resist pattern | JSR CORPORATION (JP) | 2009-04-07 | — | — | US | disclosed |
| US-20060219133-A1 | Colored resin particles, water-based dispersion containing the colored resin particles, and ink for ink-jet printing or color filter | TODA KOGYO CORPORATION (JP) | 2006-10-05 | — | — | US | disclosed |
| US-20060223008-A1 | Composition for forming antireflection film, laminate, and method for forming resist pattern | JSR CORPORATION (JP) | 2006-10-05 | — | — | US | disclosed |
| EP-1707606-A1 | Colored resin particles, water-based dispersion containing the colored resin particles, and ink for ink-jet printing or color filter | Toda Kogyo Corporation (JP) | 2006-10-04 | — | — | EP | disclosed |
| EP-1703327-A2 | Composition for forming antireflection film, laminate, and method for forming resist pattern | JSR Corporation (JP) | 2006-09-20 | — | — | EP | disclosed |