Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.32 |
| ▸ | ITGB3 known ✓ | P05106 | 4/20 | 0.32 |
| ▸ | ITGA2B known ✓ | P08514 | 3/20 | 0.32 |
| ▸ | ECE1 | P42892 | 4/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.32 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 2/20 | 0.30 |
| ▸ | CNR1 | P21554 | 2/20 | 0.30 |
| ▸ | CNR2 | P34972 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL158122 | 1.00 | ECE1 (0.39) | ECE1PLA2G2AKMT2ANPSR1ADRA1A | |
| Water SCHEMBL27080 | 1.00 | ECE1 (0.39) | ECE1PLA2G2AKMT2ANPSR1ADRA1A | |
| Water SCHEMBL6822489 | 1.00 | ECE1 (0.39) | ECE1PLA2G2AKMT2ANPSR1ADRA1A | |
| Water SCHEMBL27081 | 1.00 | ECE1 (0.39) | ECE1PLA2G2AKMT2ANPSR1ADRA1A | |
| Water SCHEMBL6822493 | 1.00 | ECE1 (0.39) | ECE1PLA2G2AKMT2ANPSR1ADRA1A | |
| SCHEMBL178169 | 0.98 | ECE1 (0.40) | ECE1PLA2G2AKMT2ANPSR1ADRA1A | |
| SCHEMBL29136617 | 0.98 | ECE1 (0.40) | ECE1PLA2G2AKMT2ANPSR1ADRA1A | |
| SCHEMBL178168 | 0.98 | ECE1 (0.40) | ECE1PLA2G2AKMT2ANPSR1ADRA1A | |
| SCHEMBL786150 | 0.98 | ECE1 (0.40) | ECE1PLA2G2AKMT2ANPSR1ADRA1A | |
| Hydrochloric Acid SCHEMBL6055023 | 0.96 | ECE1 (0.39) | ECE1PLA2G2AKMT2ANPSR1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024110873-A1 | GRAFT POLYMERIZATION OF CATIONIC MONOMERS INTO CELLULOSIC FIBERS FOR SIMULTANEOUS SUSTAINABLE DYEING AND FINISHING | NORTH CAROLINA STATE UNIVERSITY (US) | 2024-05-30 | — | — | WO | claimed |
| EP-3357935-B1 | PROCESS FOR PRODUCING WATER-ABSORBENT RESIN | SUMITOMO SEIKA CHEMICALS (JP) | 2023-07-19 | — | — | EP | claimed |
| WO-2021113960-A1 | SURFACTANT-FREE EMULSIONS OF CELLULOSE NANOCRYSTAL-POLYMER NANOCOMPOSITE AND METHOD TO PREPARE THE SAME | FPINNOVATIONS (CA) | 2021-06-17 | — | — | WO | claimed |
| US-10556975-B2 | Aqueous polymerization of thermoresponsive flocculants | PHILLIPS 66 COMPANY (US) | 2020-02-11 | — | — | US | claimed |
| US-10065173-B2 | Process for producing water-absorbent resin | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2018-09-04 | — | — | US | claimed |
| EP-3357935-A1 | PROCESS FOR PRODUCING WATER-ABSORBENT RESIN | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2018-08-08 | — | — | EP | claimed |
| EP-2993189-B1 | METHOD FOR PRODUCING WATER-ABSORBENT RESIN | SUMITOMO SEIKA CHEMICALS (JP) | 2018-04-04 | — | — | EP | claimed |
| US-20180072825-A1 | AQUEOUS POLYMERIZATION OF THERMORESPONSIVE FLOCCULANTS | PHILLIPS 66 COMPANY (US) | 2018-03-15 | — | — | US | claimed |
| EP-2692744-B1 | PROCESS FOR PRODUCING WATER-ABSORBING RESIN | SUMITOMO SEIKA CHEMICALS (JP) | 2017-08-23 | — | — | EP | claimed |
| US-9512009-B2 | Organic-inorganic silica particles, method of preparing the same, and hard coating composition containing the same | LG HAUSYS, LTD. (KR) | 2016-12-06 | — | — | US | claimed |
| EP-2616473-B1 | MIXTURES CONTAINING PHOSPHOROUS, PROCEDURES FOR THEIR PRODUCTION AND USE | CLARIANT INT LTD (CH) | 2016-11-09 | — | — | EP | claimed |
| EP-2993189-A1 | METHOD FOR PRODUCING WATER-ABSORBENT RESIN | Sumitomo Seika Chemicals Co., Ltd. (JP) | 2016-03-09 | — | — | EP | claimed |
| US-9034810-B2 | Processing agent composition for semiconductor surface and method for processing semiconductor surface using same | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2015-05-19 | — | — | US | claimed |
| EP-2692744-A1 | PROCESS FOR PRODUCING WATER-ABSORBING RESIN | Sumitomo Seika Chemicals Co., Ltd. (JP) | 2014-02-05 | — | — | EP | claimed |
| US-20260109875-A1 | MULTI-PART WATER-BORNE COATING COMPOSITION | AXALTA COATING SYSTEMS IP CO., LLC (US) | 2026-04-23 | — | — | US | disclosed |
| EP-4715042-A1 | METHOD FOR PRODUCING CELLS | Kuraray Co., Ltd. (JP) | 2026-03-25 | — | — | EP | disclosed |
| EP-4692798-A1 | TEST REAGENT INCLUDING THIOUREA COMPOUND AND RESIN PARTICLES EACH HAVING SULFUR ELEMENT, AND METHOD OF DETECTING TARGET SUBSTANCE IN SPECIMEN BY IN VITRO DIAGNOSIS USING TEST REAGENT | Canon Kabushiki Kaisha (JP) | 2026-02-11 | — | — | EP | disclosed |
| US-20070004889-A1 | Polymers based on n,n-diallylamine derivatives their production and use | BASF AKTIENGESELLSCHAFT (DE) | 2007-01-04 | — | — | US | disclosed |
| EP-1593698-A1 | The use and preparation of crosslinked polymer particles for inkjet recording materials | Hewlett-Packard Development Company, L.P. (US) | 2005-11-09 | — | — | EP | disclosed |
| US-20050019509-A1 | Calcium ion stable emulsion polymers and uses thereof | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION | 2005-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260109875-A1 | MULTI-PART WATER-BORNE COATING COMPOSITION | EGLN1, ALG1, GLO1 | ADRA1A 560/4885ITGB3 91/4885ITGA2B 208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.