Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.32 |
| ▸ | ITGB3 known ✓ | P05106 | 4/20 | 0.32 |
| ▸ | ITGA2B known ✓ | P08514 | 3/20 | 0.32 |
| ▸ | ECE1 | P42892 | 4/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.32 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 2/20 | 0.30 |
| ▸ | CNR1 | P21554 | 2/20 | 0.30 |
| ▸ | CNR2 | P34972 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL158122 | 1.00 | ECE1 (0.39) | ECE1PLA2G2AKMT2ANPSR1ADRA1A | |
| Water SCHEMBL502962 | 1.00 | ECE1 (0.39) | ECE1PLA2G2AKMT2ANPSR1ADRA1A | |
| Water SCHEMBL6822489 | 1.00 | ECE1 (0.39) | ECE1PLA2G2AKMT2ANPSR1ADRA1A | |
| Water SCHEMBL27081 | 1.00 | ECE1 (0.39) | ECE1PLA2G2AKMT2ANPSR1ADRA1A | |
| Water SCHEMBL6822493 | 1.00 | ECE1 (0.39) | ECE1PLA2G2AKMT2ANPSR1ADRA1A | |
| SCHEMBL178169 | 0.98 | ECE1 (0.40) | ECE1PLA2G2AKMT2ANPSR1ADRA1A | |
| SCHEMBL29136617 | 0.98 | ECE1 (0.40) | ECE1PLA2G2AKMT2ANPSR1ADRA1A | |
| SCHEMBL178168 | 0.98 | ECE1 (0.40) | ECE1PLA2G2AKMT2ANPSR1ADRA1A | |
| SCHEMBL786150 | 0.98 | ECE1 (0.40) | ECE1PLA2G2AKMT2ANPSR1ADRA1A | |
| Hydrochloric Acid SCHEMBL6055023 | 0.96 | ECE1 (0.39) | ECE1PLA2G2AKMT2ANPSR1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 427 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3200930-B1 | PLASMA DEPOSITION METHOD FOR CATECHOL/QUINONE FUNCTIONALISED LAYERS | LUXEMBOURG INSTITUTE OF SCIENCE AND TECH (LU) | 2023-10-04 | — | — | EP | claimed |
| US-11142603-B2 | Process for preparation of patiromer | SOLARA ACTIVE PHARMA SCIENCES LIMITED (IN) | 2021-10-12 | — | — | US | claimed |
| EP-2459607-B1 | HYBRID COPOLYMER COMPOSITIONS FOR PERSONAL CARE APPLICATIONS | NOURYON CHEMICALS INT BV (NL) | 2021-04-14 | — | — | EP | claimed |
| US-10843224-B2 | Plasma deposition method for catechol/quinone functionalised layers | LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGY (LIST) (LU) | 2020-11-24 | — | — | US | claimed |
| US-20190352442-A1 | Process for Preparation of Patiromer | SOLARA ACTIVE PHARMA SCIENCES LIMITED (IN) | 2019-11-21 | — | — | US | claimed |
| US-20170297055-A1 | Plasma Deposition Method For Catechol/Quinone Functionalised Layers | LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGY (LIST) (LU) | 2017-10-19 | — | — | US | claimed |
| WO-2017109658-A1 | PROCESS FOR THE SYNTHESIS OF PATIROMER | RJW PHARMA LLC (US) | 2017-06-29 | — | — | WO | claimed |
| US-12630502-B2 | Compounds, compositions and polymer films | FUJIFILM MANUFACTURING EUROPE B.V. (NL) | 2026-05-19 | — | — | US | disclosed |
| EP-4726006-A1 | PRESSURE-SENSITIVE ADHESIVE SHEET | Nitto Denko Corporation (JP) | 2026-04-15 | — | — | EP | disclosed |
| US-12545815-B2 | Protective sheet | NITTO DENKO CORPORATION (JP) | 2026-02-10 | — | — | US | disclosed |
| EP-3904088-B1 | PROTECTIVE SHEET | NITTO DENKO CORP (JP) | 2026-01-28 | — | — | EP | disclosed |
| US-12534583-B2 | Compositions and polymer films | FUJIFILM MANUFACTURING EUROPE B.V. (NL) | 2026-01-27 | — | — | US | disclosed |
| US-12528976-B2 | Water-dispersed pressure-sensitive adhesive composition and pressure-sensitive adhesive sheet | NITTO DENKO CORPORATION (JP) | 2026-01-20 | — | — | US | disclosed |
| US-20030087284-A1 | Virus-binding particles, virus-separating reagent, separation of viruses, and detection of viruses | JSR CORPORATION (JP) | 2003-05-08 | — | — | US | disclosed |
| EP-1218446-A4 | ADHESIVES AND METHOD FOR MAKING SAME | AVERY DENNISON CORP (US) | 2002-11-27 | — | — | EP | disclosed |
| EP-1218446-A1 | ADHESIVES AND METHOD FOR MAKING SAME | AVERY DENNISON CORPORATION (US) | 2002-07-03 | — | — | EP | disclosed |
| US-20020068805-A1 | Hollow crosslinked cationic polymer particles, method of producing said particles, and paint composition, cationic electrodeposition paint composition, resin composition, filled paper, paper coating composition, and coated paper | JSR CORPORATION (JP) | 2002-06-06 | — | — | US | disclosed |
| US-20010009759-A1 | Virus-binding particles, virus-separating reagent, separation of viruses, and detection of viruses | JSR CORPORATION (JP) | 2001-07-26 | — | — | US | disclosed |
| EP-1108743-A2 | Virus-binding particles, virus-separating reagent, separation of viruses, and detection of viruses | JSR Corporation (JP) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000068316-A1 | ADHESIVES AND METHOD FOR MAKING SAME | AVERY DENNISON CORPORATION (US) | 2000-11-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12630502-B2 | Compounds, compositions and polymer films | PHOSPHO1, SGMS1, MGMT | ADRA1A 3484/4885ITGB3 183/4885ITGA2B 1097/4885 |
| US-12534583-B2 | Compositions and polymer films | SLC9A1, SLC9A2, SLC8A1 | ADRA1A 1852/4885ITGB3 1675/4885ITGA2B 1829/4885 |
| US-12545815-B2 | Protective sheet | ACR, CDH1, ICAM1 | ADRA1A 3473/4885ITGB3 177/4885ITGA2B 112/4885 |
| US-12528976-B2 | Water-dispersed pressure-sensitive adhesive composition and pressure-sensitive adhesive sheet | EPCAM, ACTN1, CDH1 | ADRA1A 1509/4885ITGB3 170/4885ITGA2B 89/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.