SCHEMBL184464

SCHEMBL184464

O=S(=O)(Cl)c1cc(Cl)cc(Cl)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.47
ALDH1A1 P00352 3/20 0.43
HSD17B10 Q99714 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
SOD1 P00441 1/20 0.39
ACLY P53396 2/20 0.38
CYP3A4 P08684 3/20 0.38
MAPK1 P28482 1/20 0.38
FABP4 P15090 2/20 0.37
TP53 P04637 1/20 0.36
FLT1 P17948 2/20 0.36
FLT4 P35916 2/20 0.36
KDR P35968 2/20 0.36
S100A9 P06702 2/20 0.36
CYP2D6 P10635 1/20 0.36
PSEN1 P49768 1/20 0.36
PSEN2 P49810 1/20 0.36
APH1B Q8WW43 1/20 0.36
NCSTN Q92542 1/20 0.36
APH1A Q96BI3 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20241140 0.97 TSHR (0.44) TSHRALDH1A1HSD17B10TDP1SOD1
SCHEMBL1320308 0.83 ACLY (0.39) TSHRALDH1A1HSD17B10TDP1SOD1
SCHEMBL2055455 0.83 FFAR4 (0.39) ALDH1A1HSD17B10TDP1ACLYPGR
SCHEMBL13905714 0.83 CYP3A4 (0.52) TSHRALDH1A1HSD17B10TDP1CYP3A4
SCHEMBL2055456 0.83 ACLY (0.38) ALDH1A1HSD17B10TDP1ACLYPSEN1
Hydrochloric Acid SCHEMBL7571169 0.82 FBP1 (0.47) ALDH1A1HSD17B10TDP1PGR
1,3,5-Trichlorobenzene SCHEMBL4216819 0.81 TSHR (0.61) TSHRALDH1A1HSD17B10SOD1ACLY
SCHEMBL218559 0.81 ALDH1A1 (0.53) ALDH1A1HSD17B10TDP1CYP3A4MAPK1
SCHEMBL1958683 0.79 ALDH1A1 (0.52) TSHRALDH1A1HSD17B10SOD1ACLY
SCHEMBL2852652 0.78 FFAR4 (0.42) ALDH1A1CYP3A4TP53PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 925 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119425423-A Positively charged composite membrane and preparation method and application thereof 中国石油化工股份有限公司 2025-02-14 CN claimed
WO-2013102936-A1 N-(3-((DIETHYLAMINO) METHYL)-4-HYDROXYPHENYL)-N-(QUINOLIN-4-YL) SULFONAMIDES FOR THE TREATMENT OF TUBERCULOSIS AND PROCESS OF PREPARATION THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2013-07-11 WO claimed
EP-1377589-B1 OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2005-09-07 EP claimed
CN-121202849-B Coumarin-pyrazole ring hybridization derivative and preparation method and application thereof NORTHWEST UNIVERSITY (CN) 2026-05-26 CN disclosed
WO-2026107406-A1 p53 HETEROBIFUNCTIONAL CONJUGATES AND USES THEREOF Design Therapeutics, Inc. (US) 2026-05-21 WO disclosed
US-12630548-B2 Azetidine derivatives for the treatment of integrin associated diseases THE UNIVERSITY OF NOTTINGHAM (GB) 2026-05-19 US disclosed
US-12630529-B2 GCN2 modulator compounds Alesta Therapeutics BV (NL) 2026-05-19 US disclosed
US-20250381168-A1 VLA4 INHIBITORS AND USES THEREOF WASHINGTON UNIVERSITY ST LOUIS (US) 2025-12-18 US disclosed
US-20250339388-A1 PHENYLALANINE-BASED LAT1 INHIBITORS AND USES THEREOF MAXYMUNE THERAPEUTICS INC (US) 2025-11-06 US disclosed
US-20250319046-A1 PHENYLALANINE-BASED LAT1 INHIBITORS AND USES THEREOF MAXYMUNE THERAPEUTICS INC (US) 2025-10-16 US disclosed
EP-4631947-A1 SUBSTITUTED TRICYCLIC LIGANDS FOR FK506-BINDING PROTEINS FOR TREATMENT OF DISEASES Technische Universität Darmstadt (DE) 2025-10-15 EP disclosed
EP-0511826-B1 Phosphosulfonate herbicides ROHM & HAAS (US) 1997-07-16 EP disclosed
US-5500405-A Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1996-03-19 US disclosed
US-5272128-A Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1993-12-21 US disclosed
EP-0468323-B1 IMPROVED MICROCAPSULES BAYER AG (DE) 1993-09-08 EP disclosed
EP-0511826-A2 Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1992-11-04 EP disclosed
EP-0468323-A1 Improved microcapsules BAYER AG (DE) 1992-01-29 EP disclosed
US-4802910-A Herbicidal acylated sulphonylguanidines BAYER AKTIENGESELLSCHAFT (DE) 1989-02-07 US disclosed
US-4097669-A FUNGICIDES, BACTERICIDES, INSECTICIDES, ARTHROPODICIDES BAYER AKTIENGESELLSCHAFT (DT) 1978-06-27 US disclosed
US-3983300-A POLYAROMATIC SULFONE IMPERIAL CHEMICAL INDUSTRIES LIMITED (EN) 1976-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630529-B2 GCN2 modulator compounds NR3C1, GCN1, EIF2AK4 TSHR 1115/4885ALDH1A1 4260/4885HSD17B10 733/4885
US-20250339388-A1 PHENYLALANINE-BASED LAT1 INHIBITORS AND USES THEREOF SLC43A1, SLC7A1, SLC1A5 TSHR 3378/4885ALDH1A1 2745/4885HSD17B10 2654/4885
US-12630548-B2 Azetidine derivatives for the treatment of integrin associated diseases ITGA2, ITGB2, ITGB1 TSHR 104/4885ALDH1A1 814/4885HSD17B10 3114/4885
US-20250319046-A1 PHENYLALANINE-BASED LAT1 INHIBITORS AND USES THEREOF SLC43A1, SLC7A1, SLC1A5 TSHR 3378/4885ALDH1A1 2745/4885HSD17B10 2654/4885
US-20250381168-A1 VLA4 INHIBITORS AND USES THEREOF CXCR4, SDF4, ITGB4 TSHR 2581/4885ALDH1A1 523/4885HSD17B10 2928/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.