Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 14/20 | 0.44 |
| ▸ | CNR1 | P21554 | 4/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5679042 | 0.84 | BLM (0.47) | CNR2CNR1 | |
| SCHEMBL5191771 | 0.84 | CNR2 (0.46) | CNR2CNR1 | |
| SCHEMBL4979974 | 0.84 | CNR2 (0.46) | CNR2CNR1 | |
| SCHEMBL1426905 | 0.81 | CNR2 (0.43) | CNR2CNR1 | |
| SCHEMBL11318235 | 0.81 | TDP1 (0.53) | CNR2CNR1 | |
| SCHEMBL5682951 | 0.80 | CNR2 (0.43) | CNR2CNR1 | |
| SCHEMBL5682825 | 0.79 | CNR2 (0.48) | CNR2CNR1 | |
| SCHEMBL5679615 | 0.79 | ALDH1A1 (0.45) | CNR2CNR1 | |
| SCHEMBL6365435 | 0.78 | CYP3A4 (0.49) | CNR1GPR84 | |
| SCHEMBL4440332 | 0.78 | CYP3A4 (0.49) | CNR1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337566-B1 | FILMS, COMPOSITIONS AND PROCESSES | UCB SA (BE) | 2005-12-14 | — | — | EP | claimed |
| US-6969556-B2 | Films, compositions and processes | UCB, S.A. (BE) | 2005-11-29 | — | — | US | claimed |
| EP-2267044-B1 | Olefin polymer of very low polydispersity and process for preparing the same | MITSUI CHEMICALS INC (JP) | 2015-07-08 | — | — | EP | disclosed |
| EP-2267042-B1 | Olefin diblock copolymer of very low polydispersity and process for preparing the same | MITSUI CHEMICALS INC (JP) | 2015-06-10 | — | — | EP | disclosed |
| US-8436089-B2 | Polypropylene composition, a method of producing the same, and articles made therefrom | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-05-07 | — | — | US | disclosed |
| US-8338557-B2 | Olefin polymer and process for preparing the same | MITSUI CHEMICALS, INC. (JP) | 2012-12-25 | — | — | US | disclosed |
| EP-2142596-B1 | A POLYPROPYLENE COMPOSITION, A METHOD OF PRODUCING THE SAME, AND ARTICLES MADE THEREFROM | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-10-26 | — | — | EP | disclosed |
| EP-1162211-B2 | ETHYLENE (CO)POLYMERS AND USES THEREOF | MITSUI CHEMICALS INC (JP) | 2011-08-24 | — | — | EP | disclosed |
| US-20110196103-A1 | PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST | MITSUI CHEMICALS, INC. (US) | 2011-08-11 | — | — | US | disclosed |
| EP-1917304-B1 | PROPYLENE BASED RESIN COMPOSITION | MITSUI CHEMICALS INC (JP) | 2011-06-22 | — | — | EP | disclosed |
| EP-1197500-B1 | OLEFIN TRIBLOCK COPOLYMERS AND PRODUCTION PROCESSES THEREOF | MITSUI CHEMICALS INC (JP) | 2011-05-18 | — | — | EP | disclosed |
| EP-0870801-A1 | ALPHA-OLEFIN/AROMATIC VINYL COPOLYMER COMPOSITION AND MOLDINGS THEREOF | Mitsui Chemicals, Inc. (JP) | 1998-10-14 | — | — | EP | disclosed |
| EP-0869146-A1 | ETHYLENE COPOLYMER COMPOSITION AND MOLDINGS | Mitsui Chemicals, Inc. (JP) | 1998-10-07 | — | — | EP | disclosed |
| EP-0636650-B1 | Propylene polymer compositions | MITSUI PETROCHEMICAL IND (JP) | 1997-01-22 | — | — | EP | disclosed |
| US-5595827-A | BLEND WITH POLYTERPENE AND/OR PETROLEUM RESIN, MULTILAYER FILM FOR PACKAGING, WATER VAPOR BARRIER | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-21 | — | — | US | disclosed |
| EP-0634455-B1 | Polypropylene resin composition and the use of the same | MITSUI PETROCHEMICAL IND (JP) | 1997-01-08 | — | — | EP | disclosed |
| EP-0716121-A1 | Composition of polypropylene with propylene-butene elastomer | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1996-06-12 | — | — | EP | disclosed |
| US-5412020-A | Impact strength | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0636650-A1 | Propylene polymer compositions | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1995-02-01 | — | — | EP | disclosed |
| EP-0634455-A1 | Polypropylene resin composition and the use of the same | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1995-01-18 | — | — | EP | disclosed |