SCHEMBL184917

SCHEMBL184917

COc1c(Br)cccc1C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.58
ALDH1A1 P00352 5/20 0.47
KDM4E B2RXH2 4/20 0.47
HPGD P15428 3/20 0.47
MAPK1 P28482 1/20 0.47
LCK P06239 1/20 0.47
FYN P06241 1/20 0.47
PRNP P04156 1/20 0.46
APEX1 P27695 4/20 0.44
MAPT P10636 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
HTT P42858 1/20 0.44
TPMT P51580 1/20 0.43
ALOX15 P16050 1/20 0.43
MRGPRX4 Q96LA9 1/20 0.43
CASR P41180 1/20 0.43
POLB P06746 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL39857 0.86 ALDH1A1 (0.55) HSD17B10ALDH1A1KDM4EHPGDMAPK1
SCHEMBL29730967 0.85 RAB9A (0.45) HSD17B10ALDH1A1KDM4EHPGDMAPK1
SCHEMBL13091554 0.85 RAB9A (0.45) HSD17B10ALDH1A1KDM4EHPGDMAPK1
Hydrochloric Acid SCHEMBL699717 0.84 ALDH1A1 (0.53) HSD17B10ALDH1A1KDM4EHPGDMAPK1
SCHEMBL184184 0.83 LMNA (0.48) HSD17B10ALDH1A1KDM4EHPGDHTT
SCHEMBL29874691 0.83 TSHR (0.49) HSD17B10ALDH1A1KDM4EHPGDMAPT
SCHEMBL257298 0.83 TSHR (0.49) HSD17B10ALDH1A1KDM4EHPGDMAPT
SCHEMBL1515828 0.83 HSD17B10 (0.43) HSD17B10ALDH1A1KDM4EHTTALOX15
SCHEMBL78615 0.82 PRNP (0.51) HSD17B10ALDH1A1KDM4EHPGDMAPK1
SCHEMBL6215179 0.82 HSD17B10 (0.55) HSD17B10ALDH1A1KDM4EHPGDLCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104870425-B Method for synthesizing hydrazine for treating papilloma virus 阿纳孔达药业公司 2017-06-13 CN claimed
US-12630541-B2 Compounds useful as inhibitors of ALCAT 1 PERENNA PHARMACEUTICALS, INC. (US) 2026-05-19 US disclosed
EP-4603488-A1 NOVEL INDAZOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND USE THEREOF Korea University Research and Business Foundation (KR) 2025-08-20 EP disclosed
CN-120136858-A Compounds useful as ALCAT1 inhibitors 中美博瑞纳制药有限公司 2025-06-13 CN disclosed
US-20250179059-A1 ANTICANCER COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2025-06-05 US disclosed
US-20250179000-A1 METABOTROPIC GLUTAMATE RECEPTOR POSITIVE ALLOSTERIC MODULATORS (PAMS) AND USES THEREOF Sanford Burnham Prebys Medical Discovery Institute 2025-06-05 US disclosed
CN-120035587-A Novel indazole derivative or pharmaceutically acceptable salt thereof and use thereof 高丽大学校产学协力团 2025-05-23 CN disclosed
EP-4539840-A1 KINASE MODULATORS AND METHODS OF USE THEREOF Neuron23, Inc. (US) 2025-04-23 EP disclosed
CN-119730846-A Kinase modulators and methods of use thereof 神经元23公司 2025-03-28 CN disclosed
US-20250084056-A1 SUBSTITUTED OXOISOINDOLINYL PIPERIDINE-2,6-DIONE COMPOUNDS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-03-13 US disclosed
WO-2005073205-A1 SELECTIVE ESTROGEN RECEPTOR MODULATORS ELI LILLY AND COMPANY (US) 2005-08-11 WO disclosed
US-20050176684-A1 Novel aryl fructose-1,6-bisphosphatase inhibitors BOOKSER BRETT C (US) 2005-08-11 US disclosed
CN-1652779-A Combination therapy for chemokine mediated diseases SCHERING CORP (US) 2005-08-10 CN disclosed
US-6919322-B2 Phenyl Phosphonate Fructose-1,6-Bisphosphatase Inhibitors METABASIS THERAPEUTICS, INC. (US) 2005-07-19 US disclosed
EP-1485089-A1 COMBINATION TREATMENTS FOR CHEMOKINE-MEDIATED DISEASES SCHERING CORPORATION (US) 2004-12-15 EP disclosed
US-20040053953-A1 Treatment of chemokine mediated diseases SCHERING CORPORATION 2004-03-18 US disclosed
WO-2003080053-A1 COMBINATION TREATMENTS FOR CHEMOKINE-MEDIATED DISEASES SCHERING CORPORATION (US) 2003-10-02 WO disclosed
EP-1265907-A2 NOVEL ARYL FRUCTOSE-1,6-BISPHOSPHATASE INHIBITORS Metabasis Therapeutics, Inc. (US) 2002-12-18 EP disclosed
US-20020040014-A1 Novel aryl fructose-1,6-Bisphosphatase inhibitors METABASIS THERAPEUTICS, INC. 2002-04-04 US disclosed
WO-2001066553-A2 NOVEL ARYL FRUCTOSE-1,6-BISPHOSPHATASE INHIBITORS METABASIS THERAPEUTICS, INC. (US) 2001-09-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250084056-A1 SUBSTITUTED OXOISOINDOLINYL PIPERIDINE-2,6-DIONE COMPOUNDS CCNA1, CCNI, CCNE1 HSD17B10 3304/4885ALDH1A1 431/4885KDM4E 1389/4885
US-20250179059-A1 ANTICANCER COMPOUNDS BET1, BRD4, BICRA HSD17B10 3192/4885ALDH1A1 3346/4885KDM4E 682/4885
US-12630541-B2 Compounds useful as inhibitors of ALCAT 1 LCLAT1, LPCAT1, ACAT2 HSD17B10 609/4885ALDH1A1 511/4885KDM4E 3151/4885
US-20020040014-A1 Novel aryl fructose-1,6-Bisphosphatase inhibitors FBP1, SLC5A1, G6PC1 HSD17B10 511/4885ALDH1A1 228/4885KDM4E 2245/4885
US-20250179000-A1 METABOTROPIC GLUTAMATE RECEPTOR POSITIVE ALLOSTERIC MODULATORS (PAMS) AND USES THEREOF GRM3, GRM2, GRM1 HSD17B10 3733/4885ALDH1A1 4468/4885KDM4E 2197/4885
US-20040053953-A1 Treatment of chemokine mediated diseases CCR1, CXCR3, CCL11 HSD17B10 1900/4885ALDH1A1 1161/4885KDM4E 4860/4885
US-20050176684-A1 Novel aryl fructose-1,6-bisphosphatase inhibitors FBP1, G6PC1, SLC5A1 HSD17B10 615/4885ALDH1A1 341/4885KDM4E 2161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.