SCHEMBL1853657

SCHEMBL1853657

CC(=O)OC(C)OC(Oc1ccccc1CC(=O)O)C(=O)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.41
CYP3A4 P08684 1/20 0.41
CXCL8 P10145 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
CFD P00746 3/20 0.38
F11 P03951 3/20 0.38
TPSB2 P20231 3/20 0.38
LTB4R Q15722 3/20 0.36
LTB4R2 Q9NPC1 3/20 0.36
CHRM1 P11229 1/20 0.36
MMP12 P39900 1/20 0.35
PLG P00747 1/20 0.35
PLAU P00749 1/20 0.35
KLKB1 P03952 1/20 0.35
F7 P08709 1/20 0.35
AKR1B1 P15121 1/20 0.35
PTGER1 P34995 1/20 0.33
PTGER4 P35408 1/20 0.33
PTGER3 P43115 1/20 0.33
PTGER2 P43116 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21268099 0.79 ALDH1A1 (0.47) ALDH1A1CYP3A4CXCL8L3MBTL1CFD
SCHEMBL1152586 0.76 L3MBTL1 (0.45) ALDH1A1CYP3A4CXCL8L3MBTL1CFD
SCHEMBL23229157 0.76 CXCL8 (0.54) CXCL8L3MBTL1CFDF11TPSB2
SCHEMBL3941649 0.73 CXCL8 (0.54) ALDH1A1CXCL8L3MBTL1CFDF11
SCHEMBL27602776 0.70 ADRA2A (0.43) ALDH1A1L3MBTL1ADRA2AADRA2B
SCHEMBL156451 0.69 ALDH1A1 (0.65) ALDH1A1CYP3A4L3MBTL1PGRADRA2A
SCHEMBL4565147 0.69 LTB4R (0.54) CXCL8L3MBTL1CFDF11TPSB2
SCHEMBL4565149 0.69 LTB4R (0.54) CXCL8L3MBTL1CFDF11TPSB2
SCHEMBL24200105 0.69 CXCL8 (0.50) CXCL8L3MBTL1CFDF11TPSB2
SCHEMBL8086435 0.69 CXCL8 (0.50) CXCL8L3MBTL1CFDF11TPSB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1910425-B1 PHOTOPOLYMERISABLE SYSTEMS CONTAINING LOW-EXTRACTABLE AND LOW-VOLATILE COINITIATORS LAMBERTI SPA (IT) 2011-05-25 EP claimed