SCHEMBL18544299

SCHEMBL18544299

C=CC(=O)OCCCCCCCCCCCOP(=O)(O)O

nearest known ligand 0.70

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.70
ALDH1A1 P00352 3/20 0.70
CYP3A4 P08684 1/20 0.70
LPAR3 Q9UBY5 9/20 0.59
LPAR2 Q9HBW0 6/20 0.59
HPGD P15428 1/20 0.53
LPAR1 Q92633 4/20 0.50
TP53 P04637 2/20 0.48
HIF1A Q16665 2/20 0.48
HSD17B10 Q99714 1/20 0.48
THRB P10828 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1436143 1.00 TSHR (0.70) TSHRALDH1A1CYP3A4LPAR3LPAR2
SCHEMBL18544300 1.00 TSHR (0.70) TSHRALDH1A1CYP3A4LPAR3LPAR2
SCHEMBL6900882 1.00 TSHR (0.70) TSHRALDH1A1CYP3A4LPAR3LPAR2
SCHEMBL6791404 1.00 TSHR (0.70) TSHRALDH1A1CYP3A4LPAR3LPAR2
SCHEMBL6783959 1.00 TSHR (0.70) TSHRALDH1A1CYP3A4LPAR3LPAR2
SCHEMBL18544298 1.00 TSHR (0.70) TSHRALDH1A1CYP3A4LPAR3LPAR2
SCHEMBL22471730 1.00 TSHR (0.70) TSHRALDH1A1CYP3A4LPAR3LPAR2
SCHEMBL21541953 1.00 TSHR (0.70) TSHRALDH1A1CYP3A4LPAR3LPAR2
SCHEMBL22129975 1.00 TSHR (0.70) TSHRALDH1A1CYP3A4LPAR3LPAR2
SCHEMBL29365495 1.00 TSHR (0.70) TSHRALDH1A1CYP3A4LPAR3LPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 242 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3782599-B1 DENTAL POLYMERIZABLE COMPOSITION BASED ON CONDENSED SILANES VOCO GMBH (DE) 2025-09-17 EP claimed
US-12377026-B2 Dental adhesive material kit KURARAY NORITAKE DENTAL INC. (JP) 2025-08-05 US claimed
CN-119587384-A Dental ceramic prosthesis and surface modification material thereof 嘉兴市京吟生物科技有限公司 2025-03-11 CN claimed
US-11992538-B2 Polymerizable dental composition based on condensed silanes VOCO GMBH (DE) 2024-05-28 US claimed
US-12622847-B2 Organosilicon compound and dental composition containing same KURARAY NORITAKE DENTAL INC. (JP) 2026-05-12 US disclosed
EP-4736834-A1 DENTAL COMPOSITION KIT Kuraray Noritake Dental Inc. (JP) 2026-05-06 EP disclosed
EP-4725470-A1 CURABLE DENTAL COMPOSITION Kuraray Noritake Dental Inc. (JP) 2026-04-15 EP disclosed
EP-4717249-A1 DENTAL COMPOSITION Shofu Inc. (JP) 2026-04-01 EP disclosed
US-20260083644-A1 METHOD FOR PRODUCING DENTAL POLYMERIZABLE COMPOSITION OR DENTAL POLYMERIZABLE COMPOSITION INTERMEDIATE SHOFU INC (JP) 2026-03-26 US disclosed
US-20260083642-A1 DENTAL COMPOSITION SHOFU INC (JP) 2026-03-26 US disclosed
EP-3696198-B1 RESIN COMPOSITION FOR STEREOLITHOGRAPHY KURARAY NORITAKE DENTAL INC (JP) 2026-03-25 EP disclosed
US-12577340-B2 Storage stable two-component dual cure dental composition SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-03-17 US disclosed
US-10130563-B2 Dental polymerizable monomer compositions MITSUI CHEMICALS, INC. (JP) 2018-11-20 US disclosed
US-10130564-B2 Dental polymerizable monomers MITSUI CHEMICALS, INC. (JP) 2018-11-20 US disclosed
US-20180110683-A1 DENTAL POLYMERIZABLE MONOMERS, COMPOSITIONS, ADHESIVE DENTAL MATERIALS AND KITS MITSUI CHEMICALS, INC. (JP) 2018-04-26 US disclosed
EP-3278787-A1 POLYMERIZABLE MONOMER FOR DENTAL MATERIALS, COMPOSITION, ADHESIVE DENTAL MATERIAL, AND KIT Mitsui Chemicals, Inc. (JP) 2018-02-07 EP disclosed
US-20170181932-A1 DENTAL POLYMERIZABLE MONOMER COMPOSITIONS MITSUI CHEMICALS, INC. (JP) 2017-06-29 US disclosed
US-20170174621-A1 DENTAL POLYMERIZABLE MONOMERS MITSUI CHEMICALS, INC. (JP) 2017-06-22 US disclosed
EP-3135270-A1 POLYMERIZABLE MONOMER FOR DENTAL MATERIAL Mitsui Chemicals, Inc. (JP) 2017-03-01 EP disclosed
EP-3135271-A1 POLYMERIZABLE MONOMER COMPOSITION FOR DENTAL MATERIAL Mitsui Chemicals, Inc. (JP) 2017-03-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10130564-B2 Dental polymerizable monomers CAD, SMCHD1, SDAD1 TSHR 4774/4885ALDH1A1 357/4885CYP3A4 2556/4885
US-11992538-B2 Polymerizable dental composition based on condensed silanes NCAPH, RCC1, NCAPD2 TSHR 4596/4885ALDH1A1 1481/4885CYP3A4 3896/4885
US-10130563-B2 Dental polymerizable monomer compositions CAD, SMCHD1, ACR TSHR 4078/4885ALDH1A1 274/4885CYP3A4 1666/4885
US-20260083644-A1 METHOD FOR PRODUCING DENTAL POLYMERIZABLE COMPOSITION OR DENTAL POLYMERIZABLE COMPOSITION INTERMEDIATE ARCN1, LBR, POLL TSHR 3634/4885ALDH1A1 2312/4885CYP3A4 2914/4885
US-20170181932-A1 DENTAL POLYMERIZABLE MONOMER COMPOSITIONS CAD, SMCHD1, ACR TSHR 4078/4885ALDH1A1 274/4885CYP3A4 1666/4885
US-12622847-B2 Organosilicon compound and dental composition containing same MSL1, ITGA1, ITGAL TSHR 4185/4885ALDH1A1 668/4885CYP3A4 2922/4885
US-12577340-B2 Storage stable two-component dual cure dental composition GPX4, SSRP1, H1-0 TSHR 3141/4885ALDH1A1 93/4885CYP3A4 4722/4885
US-20170174621-A1 DENTAL POLYMERIZABLE MONOMERS CAD, SMCHD1, SDAD1 TSHR 4774/4885ALDH1A1 357/4885CYP3A4 2556/4885
US-20180110683-A1 DENTAL POLYMERIZABLE MONOMERS, COMPOSITIONS, ADHESIVE DENTAL MATERIALS AND KITS HRH3, HRH1, HRH2 TSHR 861/4885ALDH1A1 394/4885CYP3A4 3277/4885
US-20260083642-A1 DENTAL COMPOSITION TAS2R42, COL2A1, TAS2R1 TSHR 1588/4885ALDH1A1 1319/4885CYP3A4 4710/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.