SCHEMBL1858992

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1858556	0.86	GRIK1 (0.49)	HDAC1HDAC2HDAC3HDAC4HDAC7
	SCHEMBL1855253	0.79	L3MBTL1 (0.43)	MAPTRXFP1MMP1MMP2MMP3
	SCHEMBL1860742	0.74	HDAC3 (0.56)	HDAC1HDAC2HDAC3HDAC4HDAC7
	SCHEMBL7076099	0.72	GRIK1 (0.59)	HDAC1HDAC2HDAC3HDAC4HDAC7
	SCHEMBL22612314	0.72	MAPT (0.50)	HDAC1HDAC2HDAC3HDAC4HDAC7
	SCHEMBL3875190	0.72	HSD17B10 (0.59)	SMN1; SMN2PPARGPPARAALOX5
	SCHEMBL1585161	0.70	HSD17B10 (0.53)	SMN1; SMN2PPARGPPARAALOX5
	SCHEMBL2589952	0.70	HSD17B10 (0.53)	SMN1; SMN2PPARGPPARAALOX5
	5-Phenylvaleric Acid SCHEMBL31575763	0.70	HDAC1 (0.89)	HDAC1HDAC2HDAC3HDAC4HDAC7
	SCHEMBL3544881	0.69	GRIK1 (0.59)	HDAC1HDAC2HDAC3HDAC4HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.