Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | GRM6 | O15303 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18663310 | 0.85 | TDP1 (0.36) | TDP1THRBFGFR1FGFR2FGFR4 | |
| SCHEMBL19690414 | 0.71 | PDK2 (0.34) | TDP1THRBPDK2HSP90AA1HSP90AB1 | |
| SCHEMBL18663353 | 0.71 | TDP1 (0.44) | TDP1THRBMYCNPSR1POLB | |
| SCHEMBL18663359 | 0.69 | ALDH1A1 (0.43) | TDP1NPSR1ALDH1A1MAPTHPGD | |
| SCHEMBL28180355 | 0.68 | ALDH1A1 (0.50) | TDP1NPSR1POLBALDH1A1MAPT | |
| SCHEMBL18663367 | 0.67 | FGFR1 (0.39) | TDP1THRBFGFR1FGFR2FGFR4 | |
| SCHEMBL18663304 | 0.66 | THRB (0.64) | TDP1THRBPOLBPDK2ALDH1A1 | |
| SCHEMBL4651268 | 0.65 | ALDH1A1 (0.43) | MYCBCAT2ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8188623 | 0.64 | THRB (0.43) | TDP1THRBBCAT2ALDH1A1MAPT | |
| SCHEMBL2709811 | 0.63 | THRB (0.55) | TDP1THRBPDK2BCAT2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170088642-A1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST CONTAINING CATALYST COMPONENT AND USE THEREOF | BEIJING LIHE TECH LTD (CN) | 2017-03-30 | — | — | US | claimed |
| US-20190169328-A1 | OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF | RENQIU LIHE TECH LTD (CN) | 2019-06-06 | — | — | US | disclosed |
| US-20170355792-A1 | OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF | RENQIU LIHE TECH LTD (CN) | 2017-12-14 | — | — | US | disclosed |
| US-20170088642-A1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST CONTAINING CATALYST COMPONENT AND USE THEREOF | BEIJING LIHE TECH LTD (CN) | 2017-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170088642-A1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST CONTAINING CATALYST COMPONENT AND USE THEREOF | TEC, DGAT2, MOGAT2 | TDP1 2480/4885THRB 3945/4885FGFR1 3593/4885 |
| US-20190169328-A1 | OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF | COG2, GTF2I, POF1B | TDP1 4066/4885THRB 1623/4885FGFR1 3061/4885 |
| US-20170355792-A1 | OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF | COG2, COG7, COG4 | TDP1 3772/4885THRB 3320/4885FGFR1 3761/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.