Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18663412 | 0.82 | PDK2 (0.34) | THRBPDK2GABRA2GABRB2PTGS2 | |
| SCHEMBL18663400 | 0.72 | PDK2 (0.40) | CYP1A2CYP2C19THRBTDP1PDK2 | |
| SCHEMBL18663304 | 0.66 | THRB (0.64) | HSP90AA1HSP90AB1THRBTDP1PDK2 | |
| SCHEMBL18663305 | 0.66 | OPRK1 (0.37) | THRBTDP1KDM4EALDH1A1HPGD | |
| SCHEMBL19690707 | 0.65 | ALDH1A1 (0.41) | CYP1A2CYP2C19HSP90AA1TDP1KDM4E | |
| SCHEMBL10058354 | 0.64 | PTGS2 (0.52) | CYP1A2CYP2C19SLC6A4SLC6A3KDM4E | |
| SCHEMBL18663308 | 0.62 | TDP1 (0.38) | HSP90AA1HSP90AB1THRBTDP1PDK2 | |
| SCHEMBL18663408 | 0.62 | THRB (0.41) | THRBTDP1PDK2 | |
| SCHEMBL7536487 | 0.61 | SLC6A4 (0.61) | CYP2C19SLC6A4SLC6A3TDP1PDK2 | |
| SCHEMBL23658935 | 0.60 | PTGS2 (0.52) | CYP1A2SLC6A4SLC6A3HSP90AA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170088642-A1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST CONTAINING CATALYST COMPONENT AND USE THEREOF | BEIJING LIHE TECH LTD (CN) | 2017-03-30 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170088642-A1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST CONTAINING CATALYST COMPONENT AND USE THEREOF | TEC, DGAT2, MOGAT2 | CYP1A2 1003/4885CYP2C19 631/4885HIF1A 3785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.