Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | IL2 | P60568 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18670608 | 1.00 | RXRA (0.35) | RXRARXRBCA1CA2IL2 | |
| SCHEMBL14721995 | 0.92 | RXRB (0.42) | RXRARXRBCA1CA2IL2 | |
| SCHEMBL30821396 | 0.92 | RXRB (0.42) | RXRARXRBCA1CA2IL2 | |
| SCHEMBL14721993 | 0.92 | RXRB (0.42) | RXRARXRBCA1CA2IL2 | |
| SCHEMBL30657024 | 0.91 | GPR52 (0.35) | RXRARXRBCA1CA2IL2 | |
| SCHEMBL20492189 | 0.91 | GPR52 (0.35) | RXRARXRBCA1CA2IL2 | |
| SCHEMBL20541822 | 0.91 | PDK2 (0.32) | CA1CA2 | |
| SCHEMBL363527 | 0.90 | CA1 (0.35) | RXRARXRBCA1CA2IL2 | |
| SCHEMBL20261758 | 0.90 | CA1 (0.35) | RXRARXRBCA1CA2IL2 | |
| SCHEMBL31191616 | 0.90 | RXRB (0.44) | RXRARXRBCA1CA2IL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3601241-B1 | PESTICIDALLY ACTIVE CYCLOPROPYL METHYL AMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2022-07-27 | — | — | EP | disclosed |
| US-11388902-B2 | Pesticidally active cyclopropyl methyl amide derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2022-07-19 | — | — | US | disclosed |
| US-20210340113-A1 | PROCESS FOR PREPARATION OF OPTICALLY ENRICHED ALDOL COMPOUNDS | BASF SE (DE) | 2021-11-04 | — | — | US | disclosed |
| CN-108026090-B | Isoxazoline substituted benzamides and analogs as pesticides | 先正达参股股份有限公司 | 2021-10-26 | — | — | CN | disclosed |
| EP-3873881-A1 | PROCESS FOR PREPARATION OF OPTICALLY ENRICHED ALDOL COMPOUNDS | BASF SE (DE) | 2021-09-08 | — | — | EP | disclosed |
| EP-3353172-B1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDES AND ANALOGUES AS INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2021-02-24 | — | — | EP | disclosed |
| EP-3353172-B1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDES AND ANALOGUES AS INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2021-02-24 | — | — | EP | disclosed |
| US-20200045973-A1 | PESTICIDALLY ACTIVE CYCLOPROPYL METHYL AMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-02-13 | — | — | US | disclosed |
| US-20200045973-A1 | PESTICIDALLY ACTIVE CYCLOPROPYL METHYL AMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-02-13 | — | — | US | disclosed |
| EP-3601241-A1 | PESTICIDALLY ACTIVE CYCLOPROPYL METHYL AMIDE DERIVATIVES | Syngenta Participations AG (CH) | 2020-02-05 | — | — | EP | disclosed |
| WO-2018172471-A1 | PESTICIDALLY ACTIVE CYCLOPROPYL METHYL AMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-09-27 | — | — | WO | disclosed |
| US-20180271096-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDES AND ANALOGUES AS INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-09-27 | — | — | US | disclosed |
| EP-3353172-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDES AND ANALOGUES AS INSECTICIDES | Syngenta Participations AG (CH) | 2018-08-01 | — | — | EP | disclosed |
| WO-2017050921-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDES AND ANALOGUES AS INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-03-30 | — | — | WO | disclosed |
| WO-2017050921-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDES AND ANALOGUES AS INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-03-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11388902-B2 | Pesticidally active cyclopropyl methyl amide derivatives | ACHE, PNMT, DDT | RXRA 4260/4885RXRB 4368/4885CA1 732/4885 |
| US-20180271096-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDES AND ANALOGUES AS INSECTICIDES | CYP2E1, CYP3A7, CYP4X1 | RXRA 1824/4885RXRB 1869/4885CA1 3545/4885 |
| US-20210340113-A1 | PROCESS FOR PREPARATION OF OPTICALLY ENRICHED ALDOL COMPOUNDS | ADH5, ALDOA, ACACB | RXRA 2916/4885RXRB 2939/4885CA1 2299/4885 |
| US-20200045973-A1 | PESTICIDALLY ACTIVE CYCLOPROPYL METHYL AMIDE DERIVATIVES | ACHE, PNMT, DDT | RXRA 4260/4885RXRB 4368/4885CA1 732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.