SCHEMBL1867578

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9317096	0.89	LDHA (0.52)	ACACBLDHAEPHX1ESR1ESR2
	SCHEMBL2426124	0.84	MMP8 (0.54)	ACACBMMELDHAMEN1KMT2A
	SCHEMBL12459110	0.83	MME (0.53)	ACACBMMEMEN1NPC1RAB9A
	SCHEMBL18921686	0.83	MME (0.45)	ACACBMMEPPARGPPARALDHA
	SCHEMBL27205	0.83	LDHA (0.57)	MMEPPARGPPARALDHA
	SCHEMBL2576380	0.82	MME (0.43)	ACACBMMELDHAEPHX1ESR1
	SCHEMBL19369764	0.82	ACACB (0.47)	ACACBMMEPPARGPPARAEPHX1
	SCHEMBL22235331	0.82	KMT2A (0.53)	ACACBMMEEPHX1ESR1ESR2
	SCHEMBL3634087	0.82	ACACB (0.47)	ACACBMMEPPARGPPARAEPHX1
	SCHEMBL14355742	0.82	SLC7A5 (0.48)	ACACBMMEEPHX1ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.