SCHEMBL18720232

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25939191	0.95	MMP2 (0.54)	MMP2MMP9ALDH1A1CYP1A2CYP2C9
	SCHEMBL27676617	0.81	SMN1; SMN2 (0.64)	MMP2MMP9ALDH1A1CYP1A2CYP2C9
	SCHEMBL18720249	0.80	CASP3 (0.40)	MMP2MMP9ALDH1A1CYP1A2CYP2C9
	SCHEMBL28162376	0.77	ALDH1A1 (0.48)	MMP2MMP9ALDH1A1CYP1A2CYP2C9
	SCHEMBL5680762	0.75	CASP1 (0.66)	MMP2ALDH1A1CYP1A2CYP2C9CYP2C19
	SCHEMBL27846161	0.72	ALDH1A1 (0.38)	MMP2MMP9ALDH1A1CYP1A2CYP2C9
	SCHEMBL6562692	0.72	MMP9 (0.87)	MMP2MMP9ITGB3ITGA2B
	SCHEMBL7292677	0.72	MMP2 (0.54)	MMP2MMP9ALDH1A1CYP1A2CYP2C9
	SCHEMBL6562688	0.72	MMP9 (0.87)	MMP2MMP9ITGB3ITGA2B
	SCHEMBL18720236	0.71	MMP9 (0.61)	MMP2MMP9ITGB3ITGA2BSLC1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.