Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14980674 | 0.79 | MAPK8 (0.32) | ALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL14980641 | 0.76 | MEN1 (0.31) | ALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL13174918 | 0.65 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL14585671 | 0.60 | ADRA2A (0.36) | ALDH1A1RAB9A | |
| SCHEMBL3743443 | 0.60 | KDM4E (0.43) | ALDH1A1L3MBTL1 | |
| SCHEMBL4788947 | 0.60 | ALOX5 (0.38) | ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL28139473 | 0.59 | KDM4E (0.42) | ALDH1A1L3MBTL1 | |
| SCHEMBL28866716 | 0.58 | L3MBTL1 (0.44) | L3MBTL1 | |
| SCHEMBL21259103 | 0.58 | MEN1 (0.61) | ALDH1A1 | |
| SCHEMBL11210003 | 0.58 | FABP4 (0.38) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858999-B1 | AMIDES OF 2-AMINO-4-ARYLTHIAZOLE COMPOUNDS AND THEIR SALTS | GLENMARK PHARMACEUTICALS SA (CH) | 2017-05-10 | — | — | EP | disclosed |