Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 2/20 | 0.34 |
| ▸ | SGK1 | O00141 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4927478 | 0.91 | NOS1 (0.44) | NOS1METSGK1NPC1PIK3CA | |
| SCHEMBL4927202 | 0.80 | NOS1 (0.41) | NOS1SMN1; SMN2ALDH1A1METNPC1 | |
| SCHEMBL4151460 | 0.74 | PRKD3 (0.33) | — | |
| SCHEMBL14007184 | 0.71 | MET (0.36) | NOS1SMN1; SMN2METNPC1PDGFRB | |
| SCHEMBL4918755 | 0.70 | NOS1 (0.46) | NOS1ALDH1A1L3MBTL1METSGK1 | |
| SCHEMBL14007182 | 0.70 | MAP4K4 (0.39) | NOS1MET | |
| SCHEMBL14007181 | 0.69 | MET (0.35) | NOS1MEN1KMT2AMETNPC1 | |
| SCHEMBL5223150 | 0.68 | — | — | |
| SCHEMBL1886840 | 0.68 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1ACHE | |
| SCHEMBL1883294 | 0.68 | TOP1 (0.39) | SMN1; SMN2MEN1ALDH1A1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080280766-A1 | Pyridopyrazines for Combating Phytopathogenic Fungi | SYNGENTA CROP PROTECTION, INC. (US) | 2008-11-13 | — | — | US | disclosed |
| EP-1758901-A1 | PYRIDOPYRAZINES FOR COMBATTING PHYTOPATHOGENIC FUNGI | Syngeta Participations AG (CH) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005123733-A1 | PYRIDOPYRAZINES FOR COMBATTING PHYTOPATHOGENIC FUNGI | SYNGENTA PARTICIPATIONS AG (CH) | 2005-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280766-A1 | Pyridopyrazines for Combating Phytopathogenic Fungi | Q6ZSR9, GRHPR, PRXL2A | NOS1 1227/4885SMN1; SMN2 4223/4885MEN1 2574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.