Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | RGS4 | P49798 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.31 |
| ▸ | ELANE | P08246 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29906145 | 0.68 | GSK3A (0.37) | KMT2AKDM4EMEN1ALDH1A1GSK3A | |
| SCHEMBL7447840 | 0.66 | ACHE (0.36) | KMT2AKDM4EMEN1ALDH1A1NPSR1 | |
| SCHEMBL28859619 | 0.64 | MGLL (0.53) | KMT2AKDM4EMEN1ALDH1A1NPSR1 | |
| SCHEMBL10105148 | 0.62 | MC4R (0.40) | ACHEGSK3AGSK3BMGLLSIGMAR1 | |
| SCHEMBL2261345 | 0.61 | SLC6A2 (0.33) | KMT2AKDM4EMEN1ALDH1A1NPSR1 | |
| SCHEMBL1078286 | 0.61 | SIGMAR1 (0.48) | KMT2AKDM4EMEN1ALDH1A1GSK3A | |
| SCHEMBL14437018 | 0.59 | MGLL (0.42) | KMT2AKDM4EMEN1ALDH1A1GSK3A | |
| SCHEMBL4084451 | 0.58 | LMNA (0.45) | KDM4EALDH1A1NPSR1ACHEGSK3A | |
| SCHEMBL28659205 | 0.58 | SIGMAR1 (0.50) | KMT2AMEN1SIGMAR1MC4RELANE | |
| SCHEMBL24701942 | 0.58 | LMNA (0.39) | KMT2AKDM4EMEN1ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3002283-B1 | THIAZOLE DERIVATIVES | KYOWA HAKKO KIRIN CO LTD (JP) | 2017-06-14 | — | — | EP | disclosed |