Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 3/20 | 0.49 |
| ▸ | PDE5A | O76074 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GBA1 | P04062 | 5/20 | 0.43 |
| ▸ | CDC7 | O00311 | 1/20 | 0.42 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1898934 | 0.88 | JAK2 (0.48) | ACP1PDE5AGAANPC1RAB9A | |
| SCHEMBL1903805 | 0.84 | PDE1A (0.44) | GAANPC1RAB9AGBA1TNKS | |
| SCHEMBL1896774 | 0.82 | METAP2 (0.48) | GAANPC1RAB9AKDM4EMAPT | |
| SCHEMBL15606197 | 0.70 | PRSS12 (0.49) | ACP1NPC1RAB9A | |
| SCHEMBL27761849 | 0.70 | NPC1 (0.56) | GAANPC1RAB9AKDM4EMAPT | |
| SCHEMBL5939 | 0.68 | NPC1 (0.55) | GAANPC1RAB9AKDM4EMAPT | |
| SCHEMBL6368201 | 0.68 | NPC1 (0.55) | GAANPC1RAB9AKDM4EMAPT | |
| SCHEMBL56854 | 0.68 | RAB9A (0.55) | GAANPC1RAB9AKDM4EMAPT | |
| SCHEMBL1895948 | 0.68 | NPC1 (0.55) | GAANPC1RAB9AKDM4EMAPT | |
| SCHEMBL18300831 | 0.68 | NPC1 (0.55) | GAANPC1RAB9AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493469-A2 | PHARMACEUTICAL COMPOSITION COMPRISING INDOLE COMPOUND | LG Life Sciences Ltd (KR) | 2012-09-05 | — | — | EP | claimed |
| US-20120214804-A1 | PHARMACEUTICAL COMPOSITION COMPRISING INDOLE COMPOUND | LG CHEM, LTD. (KR) | 2012-08-23 | — | — | US | claimed |
| CN-102596198-A | Pharmaceutical composition comprising indole compound | LG LIFE SCIENCES LTD | 2012-07-18 | — | — | CN | claimed |
| WO-2011052950-A2 | PHARMACEUTICAL COMPOSITION COMPRISING INDOLE COMPOUND | LG LIFE SCIENCES LTD. (KR) | 2011-05-05 | — | — | WO | claimed |
| US-10322135-B2 | Pharmaceutical composition comprising indole compound | LG CHEM, LTD. (KR) | 2019-06-18 | — | — | US | disclosed |
| US-20170165272-A1 | PHARMACEUTICAL COMPOSITION COMPRISING INDOLE COMPOUND | LG LIFE SCIENCES LTD. (KR) | 2017-06-15 | — | — | US | disclosed |
| EP-2493469-A2 | PHARMACEUTICAL COMPOSITION COMPRISING INDOLE COMPOUND | LG Life Sciences Ltd (KR) | 2012-09-05 | — | — | EP | disclosed |
| US-20120214804-A1 | PHARMACEUTICAL COMPOSITION COMPRISING INDOLE COMPOUND | LG CHEM, LTD. (KR) | 2012-08-23 | — | — | US | disclosed |
| CN-102596198-A | Pharmaceutical composition comprising indole compound | LG LIFE SCIENCES LTD | 2012-07-18 | — | — | CN | disclosed |
| WO-2011052950-A2 | PHARMACEUTICAL COMPOSITION COMPRISING INDOLE COMPOUND | LG LIFE SCIENCES LTD. (KR) | 2011-05-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120214804-A1 | PHARMACEUTICAL COMPOSITION COMPRISING INDOLE COMPOUND | IDO1, IDO2, AIFM1 | ACP1 4666/4885PDE5A 870/4885GAA 1040/4885 |
| US-10322135-B2 | Pharmaceutical composition comprising indole compound | IDO1, IDO2, AIFM1 | ACP1 4666/4885PDE5A 870/4885GAA 1040/4885 |
| US-20170165272-A1 | PHARMACEUTICAL COMPOSITION COMPRISING INDOLE COMPOUND | TFAM, IDO1, AIFM1 | ACP1 4463/4885PDE5A 1302/4885GAA 1035/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.