Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19019922 | 0.91 | MAPK1 (0.50) | OPRK1SMN1; SMN2CHRNB2CHRNA4MAPK1 | |
| SCHEMBL19019917 | 0.89 | TDP1 (0.46) | OPRK1CHRNB2CHRNA4MAPK1PKM | |
| SCHEMBL19019834 | 0.89 | PLA2G7 (0.47) | SMN1; SMN2CHRNB2CHRNA4MAPK1PKM | |
| SCHEMBL19019870 | 0.89 | CHRNB2 (0.43) | SMN1; SMN2CHRNB2CHRNA4MAPK1LMNA | |
| SCHEMBL19061883 | 0.89 | MEN1 (0.48) | OPRK1SMN1; SMN2CHRNB2CHRNA4MAPK1 | |
| SCHEMBL19019921 | 0.86 | PKM (0.48) | SMN1; SMN2CHRNB2CHRNA4LMNAPKM | |
| SCHEMBL19019919 | 0.86 | HIF1A (0.47) | CHRNB2CHRNA4MAPK1PKMHSD17B10 | |
| SCHEMBL19061740 | 0.86 | NPC1 (0.46) | CHRNB2CHRNA4MAPK1LMNAPKM | |
| SCHEMBL19019907 | 0.85 | LMNA (0.41) | SMN1; SMN2CHRNB2CHRNA4MAPK1LMNA | |
| SCHEMBL19062037 | 0.84 | METAP2 (0.43) | CHRNB2CHRNA4MAPK1PKMHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3184549-A1 | ACYLATION OF BIOPOLYMER COMPRISING ANHYDROGLUCOSE UNITS | SAPPI Netherlands Services B.V. (NL) | 2017-06-28 | — | — | EP | disclosed |
| EP-3184514-A1 | AUTOPHAGY INHIBITORS | Deutsches Krebsforschungszentrum (DE) | 2017-06-28 | — | — | EP | disclosed |
| WO-2008025152-A1 | ANTIBACTERIAL AGENTS | MCMASTER UNIVERSITY (CA) | 2008-03-06 | — | — | WO | disclosed |