Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | GPR183 | P32249 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19061440 | 0.89 | MAPK1 (0.46) | GAANPSR1TDP1SIGMAR1OPRL1 | |
| SCHEMBL19019884 | 0.89 | MAPT (0.43) | GAANPSR1OPRL1ABCB1TP53 | |
| SCHEMBL19019923 | 0.88 | GAA (0.43) | MGAMGAASIMGAM2HPGD | |
| SCHEMBL19019905 | 0.87 | ALDH1A1 (0.40) | MGAMGAASIMGAM2POLB | |
| SCHEMBL19019870 | 0.82 | CHRNB2 (0.43) | NPSR1POLBHPGDTDP1ALDH1A1 | |
| SCHEMBL14286352 | 0.82 | OPRK1 (0.48) | POLBKMT2AOPRK1SMN1; SMN2MAPK1 | |
| SCHEMBL19062009 | 0.82 | KDM4E (0.39) | GAAPOLBALDH1A1KDM4EKMT2A | |
| SCHEMBL22263101 | 0.78 | ALDH1A1 (0.49) | GAANPSR1ALDH1A1OPRK1NPC1 | |
| SCHEMBL19019882 | 0.77 | TRPV6 (0.43) | NPSR1HPGDTDP1SIGMAR1OPRL1 | |
| SCHEMBL19061947 | 0.77 | P2RX7 (0.44) | GAAHPGDALDH1A1GFERKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3184514-A1 | AUTOPHAGY INHIBITORS | Deutsches Krebsforschungszentrum (DE) | 2017-06-28 | — | — | EP | disclosed |