Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5492632 | 0.96 | KMT2A (0.50) | KMT2AMEN1GLAALDH1A1KEAP1 | |
| SCHEMBL285412 | 0.96 | KMT2A (0.50) | KMT2AMEN1GLAALDH1A1KEAP1 | |
| Water SCHEMBL28916296 | 0.94 | KMT2A (0.49) | KMT2AMEN1GLAALDH1A1KEAP1 | |
| Potassium Ion SCHEMBL9673910 | 0.88 | KEAP1 (0.48) | KMT2AMEN1GLAALDH1A1KEAP1 | |
| SCHEMBL29463334 | 0.87 | KMT2A (0.44) | KMT2AMEN1GLAALDH1A1KEAP1 | |
| Potassium Ion SCHEMBL9897196 | 0.84 | ALOX15 (0.36) | KMT2AMEN1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL4022653 | 0.84 | KEAP1 (0.48) | KMT2AMEN1GLAALDH1A1KEAP1 | |
| SCHEMBL161682 | 0.84 | KEAP1 (0.48) | KMT2AMEN1GLAALDH1A1KEAP1 | |
| Hydrochloric Acid SCHEMBL30888463 | 0.82 | KEAP1 (0.47) | KMT2AMEN1GLAKEAP1SMN1; SMN2 | |
| SCHEMBL23780018 | 0.81 | THRB (0.40) | KMT2AMEN1ALDH1A1KEAP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118139435-A | Perovskite solar cell module with buried bottom interface modification and preparation method | 中南大学 | 2024-06-04 | — | — | CN | claimed |
| EP-4201408-B1 | CROSSLINKED CATION EXCHANGE POLYMERS, COMPOSITIONS AND USE IN TREATING HYPERKALEMIA | VIFOR INT LTD (CH) | 2025-06-25 | — | — | EP | disclosed |
| EP-4540269-A1 | METHODS AND COMPOSITIONS OF QUATERNARY IMMUNOMODULATORY NANOPARTICLES FOR MEDICAL APPLICATIONS AND IMMUNOTHERAPY | Astrid Pharma Corp. (US) | 2025-04-23 | — | — | EP | disclosed |
| US-12234260-B2 | Virus-like nanoparticles for oral delivery | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-02-25 | — | — | US | disclosed |
| CN-119451975-A | Methods and compositions of quaternary immunomodulatory nanoparticles for medical applications and immunotherapy | 艾斯特丽德制药公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-118139435-A | Perovskite solar cell module with buried bottom interface modification and preparation method | 中南大学 | 2024-06-04 | — | — | CN | disclosed |
| CN-118139435-A | Perovskite solar cell module with buried bottom interface modification and preparation method | 中南大学 | 2024-06-04 | — | — | CN | disclosed |
| WO-2023245160-A1 | METHODS AND COMPOSITIONS OF QUATERNARY IMMUNOMODULATORY NANOPARTICLES FOR MEDICAL APPLICATIONS AND IMMUNOTHERAPY | ASTRID PHARMA CORP. (US) | 2023-12-21 | — | — | WO | disclosed |
| EP-3802570-B1 | IMPROVED VIRUS-LIKE NANOPARTICLES FOR ORAL DELIVERY | UNIV CALIFORNIA (US) | 2023-10-18 | — | — | EP | disclosed |
| EP-3087176-B1 | MULTIPOTENT AND IMMUNOCOMPATIBLE STEM CELL CONCENTRATE | REGENERA MEDICINA VETERINARIA AVANCADA LTDA (BR) | 2023-09-06 | — | — | EP | disclosed |
| EP-0397753-B1 | DETERMINATION OF GENETIC SEX IN RUMINANTS USING Y-CHROMOSOME-SPECIFIC POLYNUCLEOTIDES | ADVANCED RIVERINA HOLDINGS (AU) | 1996-06-12 | — | — | EP | disclosed |
| EP-0618980-A1 | COLORIMETRIC DETERMINATION OF PEROXIDASE AND PEROXIDE | ABBOTT LABORATORIES (US) | 1994-10-12 | — | — | EP | disclosed |
| WO-1993012253-A1 | COLORIMETRIC DETERMINATION OF PEROXIDASE AND PEROXIDE | ABBOTT LABORATORIES (US) | 1993-06-24 | — | — | WO | disclosed |
| EP-0276287-B1 | SEX DETERMINATION IN RUMINANTS USING Y-CHROMOSOME SPECIFIC POLYNUCLEOTIDES | THE AUSTRALIAN NATIONAL UNIVERSITY (AU) | 1993-04-07 | — | — | EP | disclosed |
| EP-0397753-A4 | DETERMINATION OF GENETIC SEX IN RUMINANTS USING Y-CHROMOSOME-SPECIFIC POLYNUCLEOTIDES | — | 1991-06-19 | — | — | EP | disclosed |
| EP-0397753-A1 | DETERMINATION OF GENETIC SEX IN RUMINANTS USING Y-CHROMOSOME-SPECIFIC POLYNUCLEOTIDES. | ADVANCED RIVERINA HOLDINGS (AU) | 1990-11-22 | — | — | EP | disclosed |
| EP-0276287-A4 | SEX DETERMINATION IN RUMINANTS USING Y-CHROMOSOME SPECIFIC POLYNUCLEOTIDES. | UNIV AUSTRALIAN (AU) | 1989-09-19 | — | — | EP | disclosed |
| WO-1989007154-A1 | DETERMINATION OF GENETIC SEX IN RUMINANTS USING Y-CHROMOSOME-SPECIFIC POLYNUCLEOTIDES | ADVANCED RIVERINA HOLDINGS LIMITED (AU) | 1989-08-10 | — | — | WO | disclosed |
| EP-0276287-A1 | SEX DETERMINATION IN RUMINANTS USING Y-CHROMOSOME SPECIFIC POLYNUCLEOTIDES. | UNIV AUSTRALIAN (AU) | 1988-08-03 | — | — | EP | disclosed |
| WO-1988001300-A1 | SEX DETERMINATION IN RUMINANTS USING Y-CHROMOSOME SPECIFIC POLYNUCLEOTIDES | THE AUSTRALIAN NATIONAL UNIVERSITY (AU) | 1988-02-25 | — | — | WO | disclosed |