Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ABL1 | P00519 | 2/20 | 0.44 |
| ▸ | RIN1 | Q13671 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19061881 | 0.86 | TP53 (0.47) | ALDH1A1RAB9AMAPTTSHRLMNA | |
| SCHEMBL19061951 | 0.83 | NPC1 (0.46) | ALDH1A1RAB9AKMT2AMEN1TSHR | |
| SCHEMBL19019921 | 0.79 | PKM (0.48) | ALDH1A1RAB9AKMT2AMEN1TSHR | |
| SCHEMBL19019907 | 0.78 | LMNA (0.41) | ALDH1A1KMT2AMEN1ABL1RIN1 | |
| SCHEMBL19061883 | 0.77 | MEN1 (0.48) | ALDH1A1RAB9AKMT2AMEN1HSD17B10 | |
| SCHEMBL19019922 | 0.77 | MAPK1 (0.50) | ALDH1A1RAB9AKMT2AMEN1HSD17B10 | |
| SCHEMBL19062036 | 0.76 | POLB (0.44) | KMT2AMEN1HSD17B10MAPK1SMN1; SMN2 | |
| SCHEMBL19061876 | 0.76 | GFER (0.47) | ALDH1A1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL19019834 | 0.75 | PLA2G7 (0.47) | ALDH1A1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL19019870 | 0.75 | CHRNB2 (0.43) | ALDH1A1RAB9AKMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3184514-A1 | AUTOPHAGY INHIBITORS | Deutsches Krebsforschungszentrum (DE) | 2017-06-28 | — | — | EP | disclosed |