Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19061875 | 0.84 | ALDH1A1 (0.41) | HSD17B10PKMMAPK1MEN1KMT2A | |
| SCHEMBL19061885 | 0.84 | MEN1 (0.52) | HSD17B10PKMMAPK1MEN1KMT2A | |
| SCHEMBL19061887 | 0.84 | L3MBTL1 (0.51) | DAOHSD17B10PKMMAPK1MEN1 | |
| SCHEMBL19061459 | 0.84 | RAB9A (0.46) | DAOHSD17B10PKMMAPK1MEN1 | |
| SCHEMBL19019917 | 0.84 | TDP1 (0.46) | HSD17B10PKMMAPK1MEN1KMT2A | |
| SCHEMBL19019922 | 0.84 | MAPK1 (0.50) | HSD17B10PKMMAPK1MEN1KMT2A | |
| SCHEMBL19019864 | 0.82 | GFER (0.53) | DAOHSD17B10PKMMEN1KMT2A | |
| SCHEMBL19061599 | 0.82 | KDM4E (0.53) | DAOHSD17B10PKMRAB9AALDH1A1 | |
| SCHEMBL19061952 | 0.81 | CYP1A2 (0.51) | DAOHSD17B10PKMMAPK1MEN1 | |
| SCHEMBL19062037 | 0.81 | METAP2 (0.43) | HSD17B10PKMMAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3184514-A1 | AUTOPHAGY INHIBITORS | Deutsches Krebsforschungszentrum (DE) | 2017-06-28 | — | — | EP | disclosed |