Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19063261 | 0.87 | RIPK1 (0.32) | RIPK1 | |
| SCHEMBL18745664 | 0.80 | RIPK1 (0.33) | RIPK1 | |
| SCHEMBL18745690 | 0.73 | RIPK1 (0.35) | RIPK1 | |
| SCHEMBL13086721 | 0.72 | DGAT1 (0.39) | RIPK1 | |
| SCHEMBL28966034 | 0.67 | CES2 (0.39) | CES2FAAH | |
| SCHEMBL2203426 | 0.66 | TSHR (0.42) | — | |
| SCHEMBL18745663 | 0.65 | DGAT1 (0.41) | RIPK1 | |
| SCHEMBL23968802 | 0.65 | MEN1 (0.36) | — | |
| SCHEMBL19685191 | 0.64 | LMNA (0.41) | CES2FAAH | |
| SCHEMBL19509954 | 0.64 | DGAT1 (0.38) | CES2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10201546-B2 | Quinolinyl modulators of RORγt | JANSSEN PHARMACEUTICA NV (BE) | 2019-02-12 | — | — | US | disclosed |
| US-20170182056-A1 | QUINOLINYL MODULATORS OF RORyt | JANSSEN PHARMACEUTICA NV (BE) | 2017-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10201546-B2 | Quinolinyl modulators of RORγt | RORC, RORB, RORA | CES2 4208/4885RIPK1 1762/4885FAAH 2263/4885 |
| US-20170182056-A1 | QUINOLINYL MODULATORS OF RORyt | RORC, RORA, RORB | CES2 4144/4885RIPK1 1415/4885FAAH 2744/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.