Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19068172 | 0.85 | KMT2A (0.57) | HTR3ALMNASMN1; SMN2HTR6KMT2A | |
| SCHEMBL6674814 | 0.80 | AKR1C3 (0.62) | HTR3ALMNASMN1; SMN2HTR6KMT2A | |
| SCHEMBL17176310 | 0.80 | SMN1; SMN2 (0.70) | HTR3ALMNASMN1; SMN2HTR6KMT2A | |
| SCHEMBL6672345 | 0.79 | FABP4 (0.55) | HTR3ALMNASMN1; SMN2HTR6KMT2A | |
| SCHEMBL17170611 | 0.77 | ALDH1A1 (0.56) | HTR3ALMNASMN1; SMN2HTR6KMT2A | |
| SCHEMBL22289917 | 0.73 | HTR3A (0.56) | HTR3ALMNASMN1; SMN2HTR6KMT2A | |
| SCHEMBL7671291 | 0.72 | HTR6 (0.66) | HTR6 | |
| SCHEMBL27622290 | 0.70 | LMNA (0.72) | LMNASMN1; SMN2HTR6KMT2APLK1 | |
| SCHEMBL2692814 | 0.70 | HTR6 (0.59) | HTR3ALMNASMN1; SMN2HTR6KMT2A | |
| SCHEMBL17176299 | 0.69 | SMN1; SMN2 (0.67) | HTR3ALMNASMN1; SMN2HTR6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9695195-B2 | 5-HT3 receptor antagonists | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2017-07-04 | — | — | US | disclosed |