Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 8/20 | 0.34 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19087203 | 0.89 | MMP1 (0.39) | ALDH1A1RENPPARGPTGESALOX5 | |
| SCHEMBL19087186 | 0.81 | ALDH1A1 (0.37) | KDM4EMAPTMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL17265982 | 0.78 | MMP1 (0.40) | MAPTATMALDH1A1RENPPARG | |
| SCHEMBL17732271 | 0.76 | REN (0.40) | ALDH1A1SMN1; SMN2RENPPARGPPARD | |
| SCHEMBL16981217 | 0.75 | KDM4E (0.37) | KDM4EMAPTMAPK1ATMALDH1A1 | |
| SCHEMBL19087185 | 0.73 | REN (0.42) | ALDH1A1SMN1; SMN2REN | |
| SCHEMBL19087120 | 0.72 | REN (0.39) | RENPPARGPTGESALOX5 | |
| SCHEMBL17721709 | 0.72 | REN (0.37) | MAPTMAPK1ALDH1A1SMN1; SMN2REN | |
| SCHEMBL20059002 | 0.71 | REN (0.42) | REN | |
| SCHEMBL19087147 | 0.71 | SIGMAR1 (0.45) | KDM4ERENLDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017114812-A1 | COMBINATION THERAPY OF AN HBSAG INHIBITOR AND AN INTERFERON | F. HOFFMANN-LA ROCHE AG (CH) | 2017-07-06 | — | — | WO | disclosed |