Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 4/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.66 |
| ▸ | TTR | P02766 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | APP | P05067 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.62 |
| ▸ | DPP4 | P27487 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.62 |
| ▸ | CA12 | O43570 | 1/20 | 0.62 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MMP1 | P03956 | 1/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19078812 | 0.86 | BACE1 (0.59) | IAPPPTGS1TTRKDM4EHSD17B10 | |
| SCHEMBL20457624 | 0.83 | IAPP (0.62) | IAPPPTGS1TTRKDM4EHSD17B10 | |
| SCHEMBL3136872 | 0.82 | KMT2A (0.68) | KDM4EKMT2AMAPTDPP4MEN1 | |
| SCHEMBL4821062 | 0.82 | KMT2A (0.68) | KDM4EKMT2AMAPTDPP4MEN1 | |
| SCHEMBL10001150 | 0.82 | KMT2A (0.78) | PTGS1KDM4EHSD17B10APPKMT2A | |
| SCHEMBL1881134 | 0.79 | IAPP (1.00) | IAPPPTGS1TTRKDM4EHSD17B10 | |
| SCHEMBL1881133 | 0.79 | IAPP (1.00) | IAPPPTGS1TTRKDM4EHSD17B10 | |
| SCHEMBL21235162 | 0.79 | TYR (0.61) | KMT2AMAPTDPP4MEN1HDAC3 | |
| SCHEMBL29364807 | 0.79 | IAPP (1.00) | IAPPPTGS1TTRKDM4EHSD17B10 | |
| SCHEMBL23854648 | 0.79 | HSD17B10 (0.64) | IAPPPTGS1TTRKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220348530-A1 | Menaquinol Compositions and Methods of Treatment | Epizon Pharma, Inc. (US) | 2022-11-03 | — | — | US | disclosed |
| US-11332427-B2 | Menaquinol compositions and methods of treatment | Epizon Pharma, Inc. (US) | 2022-05-17 | — | — | US | disclosed |
| US-20210009494-A1 | Menaquinol Compositions and Methods of Treatment | Epizon Pharma, Inc. (US) | 2021-01-14 | — | — | US | disclosed |
| US-10822295-B2 | Menaquinol compositions and methods of treatment | Epizon Pharma, Inc. (US) | 2020-11-03 | — | — | US | disclosed |
| US-10426717-B2 | Glycol esters of dicaffeoylquinic acid and uses thereof | PLANT ADVANCED TECHNOLOGIES PAT (FR) | 2019-10-01 | — | — | US | disclosed |
| US-20190038533-A1 | GLYCOL ESTERS OF DICAFFEOYLQUINIC ACID AND USES THEREOF | PLANT ADVANCED TECHNOLOGIES PAT (FR) | 2019-02-07 | — | — | US | disclosed |
| US-20170188606-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR REDUCING OR ELIMINATING BITTER TASTE | CHROMOCELL CORP (US) | 2017-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10426717-B2 | Glycol esters of dicaffeoylquinic acid and uses thereof | RECQL, POLQ, DCLRE1A | IAPP 4380/4885PTGS1 213/4885TTR 3516/4885 |
| US-20210009494-A1 | Menaquinol Compositions and Methods of Treatment | SDHA, SDHB, NDUFB7 | IAPP 4684/4885PTGS1 781/4885TTR 2726/4885 |
| US-20170188606-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR REDUCING OR ELIMINATING BITTER TASTE | TAS2R5, TAS2R20, TAS2R4 | IAPP 29/4885PTGS1 2963/4885TTR 2796/4885 |
| US-20190038533-A1 | GLYCOL ESTERS OF DICAFFEOYLQUINIC ACID AND USES THEREOF | RECQL, POLQ, DCLRE1A | IAPP 4380/4885PTGS1 213/4885TTR 3516/4885 |
| US-20220348530-A1 | Menaquinol Compositions and Methods of Treatment | SDHA, SDHB, NDUFB7 | IAPP 4684/4885PTGS1 781/4885TTR 2726/4885 |
| US-11332427-B2 | Menaquinol compositions and methods of treatment | SDHA, SDHB, NDUFB7 | IAPP 4684/4885PTGS1 781/4885TTR 2726/4885 |
| US-10822295-B2 | Menaquinol compositions and methods of treatment | PROC, VKORC1L1, VKORC1 | IAPP 4010/4885PTGS1 975/4885TTR 4018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.