SCHEMBL19146554

SCHEMBL19146554

C=C(C)C(=O)NCCCCCCN1CCCCCC1=O

nearest known ligand 0.51

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 7/20 0.51
NPC1 O15118 4/20 0.51
KMT2A Q03164 3/20 0.46
ATM Q13315 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.43
MEN1 O00255 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19146541 0.95 RAB9A (0.56) RAB9ANPC1KMT2AATMSMN1; SMN2
SCHEMBL19145899 0.89 KMT2A (0.57) RAB9ANPC1KMT2AATMSMN1; SMN2
SCHEMBL19145900 0.84 KMT2A (0.64) RAB9ANPC1KMT2AATMSMN1; SMN2
SCHEMBL24621731 0.82 RAB9A (0.52) RAB9ANPC1KMT2ASMN1; SMN2L3MBTL1
SCHEMBL8064632 0.81 KMT2A (0.42) RAB9ANPC1KMT2ASMN1; SMN2L3MBTL1
SCHEMBL19146013 0.81 RAB9A (0.46) RAB9ANPC1KMT2ASMN1; SMN2L3MBTL1
SCHEMBL23034881 0.78 TDP1 (0.49) RAB9ANPC1KMT2ASMN1; SMN2L3MBTL1
SCHEMBL19146019 0.77 TSHR (0.47) RAB9ANPC1KMT2ASMN1; SMN2L3MBTL1
SCHEMBL19159431 0.76 KMT2A (0.40) RAB9ANPC1KMT2AMEN1
SCHEMBL19807923 0.76 BLM (0.45) RAB9ANPC1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11912831-B2 Hydroxyethylpyrrolidone ethacrylate/glycidyl ethacrylate copolymers ISP INVESTMENTS LLC (US) 2024-02-27 US disclosed
US-11912831-B2 Hydroxyethylpyrrolidone ethacrylate/glycidyl ethacrylate copolymers ISP INVESTMENTS LLC (US) 2024-02-27 US disclosed
US-11859029-B2 Methods of synthesis of homopolymers and non-homopolymers comprising repeating units derived from monomers comprising lactam and acryloyl moieties in an aqueous medium ISP INVESTMENTS LLC (US) 2024-01-02 US disclosed
US-11859029-B2 Methods of synthesis of homopolymers and non-homopolymers comprising repeating units derived from monomers comprising lactam and acryloyl moieties in an aqueous medium ISP INVESTMENTS LLC (US) 2024-01-02 US disclosed
US-11001751-B2 Crosslinked polymers derived from monomers having acryloyl and lactam moieties and sulfonic acid/sulfonate comonomers, compositions thereof, and applications thereof HERCULES LLC (US) 2021-05-11 US disclosed
US-10905636-B2 Block copolymers comprising repeating units derived from monomers comprising lactam and acryloyl moieties and hydrophobic monomers, compositions, and applications thereof ISP INVESTMENTS LLC (US) 2021-02-02 US disclosed
US-20200407470-A1 METHODS OF SYNTHESIS OF HOMOPOLYMERS AND NON-HOMOPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES IN AN AQUEOUS MEDIUM ISP INVESTMENTS LLC (US) 2020-12-31 US disclosed
US-10876015-B2 Coating compositions for forming toner coatings ISP INVESTMENTS LLC (US) 2020-12-29 US disclosed
US-10865264-B2 Hydroxyethylpyrrolidone methacrylate/glycidyl methacrylate copolymers ISP INVESTMENTS LLC (US) 2020-12-15 US disclosed
US-10844154-B2 Proliferous copolymers comprising lactamic moieties ISP INVESTMENTS LLC (US) 2020-11-24 US disclosed
US-10765617-B2 Personal care compositions comprising copolymers of cationic monomers and acryloyl lactam based monomers, process for the same and method of use ISP INVESTMENTS LLC (US) 2020-09-08 US disclosed
US-10745502-B2 Polymers for oral care compositions ISP INVESTMENTS LLC (US) 2020-08-18 US disclosed
US-10632059-B2 Non-aqueous compositions of polymers derived from monomers having acryloyl moiety and lactam moiety and applications thereof ISP INVESTMENTS LLC (US) 2020-04-28 US disclosed
US-20190382519-A1 CROSS-LINKED BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES, COMPOSITIONS, AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2019-12-19 US disclosed
US-20190151224-A1 PERSONAL CARE COMPOSITIONS COMPRISING COPOLYMERS OF CATIONIC MONOMERS AND ACRYLOYL LACTAM BASED MONOMERS, PROCESS FOR THE SAME AND METHOD OF USE ISP INVESTMENTS LLC (US) 2019-05-23 US disclosed
US-20190015304-A1 BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES AND HYDROPHOBIC MONOMERS, COMPOSITIONS, AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2019-01-17 US disclosed
WO-2018132370-A1 HIGH MOLECULAR WEIGHT BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES AND HYDROPHILIC MONOMERS, COMPOSITIONS, AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2018-07-19 WO disclosed
WO-2018132548-A1 CROSS-LINKED BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES, COMPOSITIONS, AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2018-07-19 WO disclosed
WO-2018017570-A1 A HAIR STRAIGHTENING AND STYLING COMPOSITION, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF ISP INVESTMENTS LLC (US) 2018-01-25 WO disclosed
WO-2017123572-A1 BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES AND HYDROPHOBIC MONOMERS, COMPOSITIONS, AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2017-07-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10745502-B2 Polymers for oral care compositions SMARCC1, MPO, ARID2 RAB9A 2573/4885NPC1 4340/4885KMT2A 728/4885
US-11912831-B2 Hydroxyethylpyrrolidone ethacrylate/glycidyl ethacrylate copolymers MMAB, PCNA, HMBS RAB9A 3875/4885NPC1 4879/4885KMT2A 1105/4885
US-10632059-B2 Non-aqueous compositions of polymers derived from monomers having acryloyl moiety and lactam moiety and applications thereof C9, PARG, C5 RAB9A 3191/4885NPC1 1847/4885KMT2A 3840/4885
US-20190015304-A1 BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES AND HYDROPHOBIC MONOMERS, COMPOSITIONS, AND APPLICATIONS THEREOF F9, ADCY9, MMS19 RAB9A 217/4885NPC1 3655/4885KMT2A 4458/4885
US-10905636-B2 Block copolymers comprising repeating units derived from monomers comprising lactam and acryloyl moieties and hydrophobic monomers, compositions, and applications thereof F9, ADCY9, MMS19 RAB9A 217/4885NPC1 3655/4885KMT2A 4458/4885
US-11001751-B2 Crosslinked polymers derived from monomers having acryloyl and lactam moieties and sulfonic acid/sulfonate comonomers, compositions thereof, and applications thereof CAD, STS, COASY RAB9A 4498/4885NPC1 3343/4885KMT2A 3224/4885
US-10844154-B2 Proliferous copolymers comprising lactamic moieties PCNA, MKI67, CCNA1 RAB9A 4179/4885NPC1 4195/4885KMT2A 1923/4885
US-10765617-B2 Personal care compositions comprising copolymers of cationic monomers and acryloyl lactam based monomers, process for the same and method of use AADAC, KRT18, AAAS RAB9A 2512/4885NPC1 4393/4885KMT2A 807/4885
US-20190382519-A1 CROSS-LINKED BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES, COMPOSITIONS, AND APPLICATIONS THEREOF ADSL, ABHD6, APH1B RAB9A 4363/4885NPC1 3260/4885KMT2A 3944/4885
US-20190151224-A1 PERSONAL CARE COMPOSITIONS COMPRISING COPOLYMERS OF CATIONIC MONOMERS AND ACRYLOYL LACTAM BASED MONOMERS, PROCESS FOR THE SAME AND METHOD OF USE AADAC, KRT18, AAAS RAB9A 2512/4885NPC1 4393/4885KMT2A 807/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.