Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 3/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19166902 | 0.90 | GPR84 (0.49) | GPR84PTGS2CYP3A4ALDH1A1RARB | |
| SCHEMBL19166233 | 0.89 | GPR84 (0.47) | GPR84PTGS2CYP3A4ALDH1A1RARB | |
| SCHEMBL17672771 | 0.88 | ALDH1A1 (0.54) | GPR84PTGS2CYP3A4ALDH1A1RARB | |
| SCHEMBL17672982 | 0.85 | GPR84 (0.67) | GPR84PTGS2CYP3A4ALDH1A1RARB | |
| SCHEMBL19166809 | 0.83 | GPR84 (0.51) | GPR84PTGS2CYP3A4ALDH1A1ALOX5 | |
| SCHEMBL19542666 | 0.83 | BID (0.48) | PTGS2ALDH1A1ALOX5MAPTALOX15 | |
| SCHEMBL19166230 | 0.81 | PTGS2 (0.50) | GPR84PTGS2CYP3A4ALDH1A1TP53 | |
| SCHEMBL16050400 | 0.81 | ALDH1A1 (0.57) | GPR84CYP3A4ALDH1A1RARBRARA | |
| SCHEMBL17672767 | 0.80 | PTGS2 (0.48) | GPR84PTGS2CYP3A4ALDH1A1MEN1 | |
| SCHEMBL16050565 | 0.79 | ALDH1A1 (0.56) | GPR84CYP3A4ALDH1A1RARBRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170312237-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR TISSUE SELF-REPAIR AND REGENERATION | Liminal Biosciences Limited (GB) | 2017-11-02 | — | — | US | disclosed |
| US-20170209399-A1 | Substituted Aromatic Compounds and Pharmaceutical Compositions For The Prevention And Treatment Of Diabetes | PROMETIC PHARMA SMT LIMITED (GB) | 2017-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170312237-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR TISSUE SELF-REPAIR AND REGENERATION | CCNH, COL1A1, COL2A1 | GPR84 2125/4885PTGS2 263/4885CYP3A4 2283/4885 |
| US-20170209399-A1 | Substituted Aromatic Compounds and Pharmaceutical Compositions For The Prevention And Treatment Of Diabetes | GPR119, LIPC, INSR | GPR84 1382/4885PTGS2 2425/4885CYP3A4 571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.