Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 5/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8351216 | 0.75 | TRPA1 (0.38) | NOS3NOS1NOS2CYP1A2TRPA1 | |
| SCHEMBL334119 | 0.75 | TRPA1 (0.42) | NOS3NOS1NOS2CYP1A2TRPA1 | |
| SCHEMBL6682029 | 0.71 | TRPA1 (0.35) | NOS3NOS1NOS2TRPA1SIGMAR1 | |
| SCHEMBL84394 | 0.67 | NOS3 (0.65) | NOS3NOS1NOS2CYP1A2TRPA1 | |
| SCHEMBL9924581 | 0.67 | NOS3 (0.43) | NOS3NOS1NOS2CYP1A2TRPA1 | |
| SCHEMBL3616940 | 0.67 | NOS3 (0.48) | NOS3NOS1NOS2CYP1A2TRPA1 | |
| SCHEMBL35438 | 0.67 | NOS3 (0.48) | NOS3NOS1NOS2CYP1A2TRPA1 | |
| SCHEMBL124176 | 0.67 | CYP1A2 (0.44) | NOS3NOS1NOS2CYP1A2TRPA1 | |
| SCHEMBL14454718 | 0.67 | NOS3 (0.44) | NOS3NOS1NOS2CYP1A2TRPA1 | |
| SCHEMBL5021700 | 0.66 | NOS3 (0.46) | NOS3NOS1NOS2TRPA1PDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116655618-A | Probes for imaging huntingtin | CHDI基金会股份有限公司 | 2023-08-29 | — | — | CN | claimed |
| EP-4006016-A2 | PROBES FOR IMAGING HUNTINGTIN PROTEIN | CHDI Foundation, Inc. (US) | 2022-06-01 | — | — | EP | claimed |
| US-11059836-B2 | Probes for imaging huntingtin protein | CHDI FOUNDATION, INC. (US) | 2021-07-13 | — | — | US | claimed |
| US-20200102328-A1 | PROBES FOR IMAGING HUNTINGTIN PROTEIN | EVOTEC (UK) LTD. (GB) | 2020-04-02 | — | — | US | claimed |
| US-20170283436-A1 | PROBES FOR IMAGING HUNTINGTIN PROTEIN | EVOTEC (UK) LTD. (GB) | 2017-10-05 | — | — | US | claimed |
| EP-3186233-A1 | PROBES FOR IMAGING HUNTINGTIN PROTEIN | CHDI Foundation, Inc. (US) | 2017-07-05 | — | — | EP | claimed |
| WO-2016033445-A1 | PROBES FOR IMAGING HUNTINGTIN PROTEIN | CHDI FOUNDATION, INC. (US) | 2016-03-03 | — | — | WO | claimed |
| US-8552023-B2 | Non-amidic linkers with branched termini as CGRP receptor antagonists | MERCK SHARP & DOHME CORP. (US) | 2013-10-08 | — | — | US | claimed |
| EP-2326176-B1 | NON-AMIDIC LINKERS WITH BRANCHED TERMINI AS CGRP RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME (US) | 2013-09-18 | — | — | EP | claimed |
| US-20110190329-A1 | NON-AMIDIC LINKERS WITH BRANCHED TERMINI AS CGRP RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME LLC | 2011-08-04 | — | — | US | claimed |
| EP-2326176-A1 | NON-AMIDIC LINKERS WITH BRANCHED TERMINI AS CGRP RECEPTOR ANTAGONISTS | Merck Sharp & Dohme Corp. (US) | 2011-06-01 | — | — | EP | claimed |
| WO-2010021864-A1 | NON-AMIDIC LINKERS WITH BRANCHED TERMINI AS CGRP RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME CORP. (US) | 2010-02-25 | — | — | WO | claimed |
| EP-2148859-A1 | 5-LIPOXYGENASE-ACTIVATING PROTEIN (FLAP) INHIBITORS | Amira Pharmaceuticals, Inc. (US) | 2010-02-03 | — | — | EP | claimed |
| EP-2144875-A1 | 5-LIPOXYGENASE-ACTIVATING PROTEIN (FLAP) INHIBITORS | Amira Pharmaceuticals, Inc. (US) | 2010-01-20 | — | — | EP | claimed |
| WO-2008137805-A1 | 5-LIPOXYGENASE-ACTIVATING PROTEIN (FLAP) INHIBITORS | AMIRA PHARMACEUTICALS, INC. (US) | 2008-11-13 | — | — | WO | claimed |
| WO-2008137609-A1 | 5-LIPOXYGENASE-ACTIVATING PROTEIN (FLAP) INHIBITORS | AMIRA PHARMACEUTICALS, INC. (US) | 2008-11-13 | — | — | WO | claimed |
| US-4545806-A | 5-(Oxo or thio heterocycle) cyclohexane-1,3-dione derivatives and their use for controlling undesirable plant growth | BASF AKTIENGESELLSCHAFT (DE) | 1985-10-08 | — | — | US | claimed |
| US-20240231224-A9 | HALOGEN-AND ALIPHATIC-CONTAINING ORGANOTIN PHOTORESISTS AND METHODS THEREOF | LAM RESEARCH CORPORATION | 2024-07-11 | — | — | US | disclosed |
| EP-0189774-A1 | Process for production of N,N-disubstituted carboxylic acid amides | TOKUYAMA SODA KABUSHIKI KAISHA (JP) | 1986-08-06 | — | — | EP | disclosed |
| US-4545806-A | 5-(Oxo or thio heterocycle) cyclohexane-1,3-dione derivatives and their use for controlling undesirable plant growth | BASF AKTIENGESELLSCHAFT (DE) | 1985-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11059836-B2 | Probes for imaging huntingtin protein | HTT, HYPK, HSPBP1 | NOS3 4739/4885NOS1 4602/4885NOS2 4732/4885 |
| US-20200102328-A1 | PROBES FOR IMAGING HUNTINGTIN PROTEIN | HTT, HYPK, HSPBP1 | NOS3 4739/4885NOS1 4602/4885NOS2 4732/4885 |
| US-20170283436-A1 | PROBES FOR IMAGING HUNTINGTIN PROTEIN | HTT, HYPK, FABP7 | NOS3 4707/4885NOS1 4582/4885NOS2 4693/4885 |
| US-20110190329-A1 | NON-AMIDIC LINKERS WITH BRANCHED TERMINI AS CGRP RECEPTOR ANTAGONISTS | CALCRL, GRPR, CCKBR | NOS3 990/4885NOS1 1482/4885NOS2 1688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.