Sugi Predict

Sugi Predict / Compounds / SCHEMBL1924441

SCHEMBL1924441

SCHEMBL1924441

CC(C)C(CNC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ KCNA3 P22001 1/20 0.65
▸ NPC1 O15118 2/20 0.65
▸ RAB9A P51151 2/20 0.65
▸ SMN1; SMN2 Q16637 1/20 0.65
▸ GPR139 Q6DWJ6 2/20 0.56
▸ EPHX2 P34913 1/20 0.56
▸ GAA P10253 2/20 0.53
▸ KMT2A Q03164 1/20 0.53
▸ HSD17B10 Q99714 1/20 0.53
▸ TACR1 P25103 1/20 0.50
▸ LMNA P02545 1/20 0.49
▸ POLB P06746 1/20 0.49
▸ TAAR1 Q96RJ0 1/20 0.47
▸ HDAC1 Q13547 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2481230 0.84 NPC1 (0.67) NPC1RAB9ASMN1; SMN2GPR139EPHX2
SCHEMBL5709362 0.84 NPC1 (0.67) NPC1RAB9ASMN1; SMN2GPR139EPHX2
SCHEMBL28002063 0.82 KCNA3 (0.57) KCNA3NPC1RAB9ASMN1; SMN2GPR139
SCHEMBL15273138 0.82 NPC1 (0.59) NPC1RAB9ASMN1; SMN2GPR139EPHX2
SCHEMBL28820759 0.82 NPC1 (0.59) NPC1RAB9ASMN1; SMN2GPR139EPHX2
SCHEMBL31530566 0.82 NPC1 (0.73) NPC1RAB9ASMN1; SMN2GPR139EPHX2
SCHEMBL255251 0.82 GAA (0.76) NPC1RAB9ASMN1; SMN2GPR139EPHX2
SCHEMBL19557264 0.81 KCNA3 (0.56) KCNA3NPC1RAB9ASMN1; SMN2GPR139
SCHEMBL19334001 0.81 SMN1; SMN2 (0.62) NPC1RAB9ASMN1; SMN2GPR139EPHX2
SCHEMBL8506869 0.80 NPC1 (0.66) NPC1RAB9ASMN1; SMN2GPR139EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11495755-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-11-08 — — US disclosed
EP-3719099-A1 PHOSPHORESCENT MATERIALS Universal Display Corporation (US) 2020-10-07 — — EP disclosed
US-20200176693-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-06-04 — — US disclosed
EP-3327100-B1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORP (US) 2020-05-06 — — EP disclosed
US-10600975-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-03-24 — — US disclosed
US-20190157576-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-05-23 — — US disclosed
US-10230060-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-03-12 — — US disclosed
EP-3404736-A1 PHOSPHORESCENT MATERIALS Universal Display Corporation (US) 2018-11-21 — — EP disclosed
US-10084143-B2 Phosphorescent materials UNIVERSAL DISPLAY CORPORATION (US) 2018-09-25 — — US disclosed
EP-2999021-B1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORP (US) 2018-08-08 — — EP disclosed
EP-2121871-B1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORP (US) 2013-08-14 — — EP disclosed
US-8431243-B2 Substituted 2-Phenyl quinoline complex with Iridium; high device efficiency, stability, and processibility UNIVERSAL DISPLAY CORPORATION (US) 2013-04-30 — — US disclosed
EP-2489716-A2 Phosphorescent materials Universal Display Corporation (US) 2012-08-22 — — EP disclosed
EP-2465912-A1 Phosphorescent Materials Universal Display Corporation (US) 2012-06-20 — — EP disclosed
EP-2329541-A1 PHOSPHORESCENT MATERIALS Universal Display Corporation (US) 2011-06-08 — — EP disclosed
US-20100090591-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2010-04-15 — — US disclosed
WO-2010033550-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2010-03-25 — — WO disclosed
EP-2121871-A2 PHOSPHORESCENT MATERIALS University Display Corporation (US) 2009-11-25 — — EP disclosed
US-20080261076-A1 Substituted 2-Phenyl quinoline complex with Iridium; high device efficiency, stability, and processibility UNIVERSAL DISPLAY CORPORATION (US) 2008-10-23 — — US disclosed
WO-2008109824-A2 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2008-09-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080261076-A1 Substituted 2-Phenyl quinoline complex with Iridium; high device efficiency, stability, and processibility PCID2, ICMT, ORAI2 KCNA3 1740/4885NPC1 3616/4885RAB9A 1685/4885
US-20200176693-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES RUVBL2, TERT, OR10J3 KCNA3 95/4885NPC1 4327/4885RAB9A 1698/4885
US-11495755-B2 Organic electroluminescent materials and devices RUVBL2, TERT, OR10J3 KCNA3 95/4885NPC1 4327/4885RAB9A 1698/4885
US-10230060-B2 Organic electroluminescent materials and devices RUVBL2, OR10J3, EML4 KCNA3 213/4885NPC1 4152/4885RAB9A 2028/4885
US-10600975-B2 Organic electroluminescent materials and devices TERT, OR10J3, RUVBL2 KCNA3 114/4885NPC1 4327/4885RAB9A 1716/4885
US-20100090591-A1 PHOSPHORESCENT MATERIALS PPA1, PHOSPHO1, PPP1CC KCNA3 3457/4885NPC1 2727/4885RAB9A 1459/4885
US-20190157576-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES PIEZO1, ORAI2, PORCN KCNA3 625/4885NPC1 3813/4885RAB9A 2720/4885
US-10084143-B2 Phosphorescent materials PPA1, MTAP, NES KCNA3 2588/4885NPC1 3079/4885RAB9A 2679/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.