Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 9/20 | 0.61 |
| ▸ | HTR1A | P08908 | 2/20 | 0.54 |
| ▸ | HTR2A | P28223 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1927006 | 0.92 | HTR7 (0.63) | HTR7HTR1AHTR2AKDM4EALDH1A1 | |
| SCHEMBL6527413 | 0.89 | KDM4E (0.58) | HTR7KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6521520 | 0.82 | MEN1 (0.58) | HTR7HTR1AHTR2AKDM4EHRH3 | |
| SCHEMBL6096262 | 0.79 | HTR7 (0.60) | HTR7HTR1AHTR2AKDM4EALDH1A1 | |
| SCHEMBL6521382 | 0.77 | HTR7 (0.61) | HTR7HTR1AHTR2AKDM4EALDH1A1 | |
| SCHEMBL12685359 | 0.76 | TDP1 (0.59) | HTR7HTR1AHTR2AHRH3MEN1 | |
| SCHEMBL7253798 | 0.76 | L3MBTL1 (0.71) | HTR7HTR1AHTR2AKDM4EALDH1A1 | |
| SCHEMBL29865235 | 0.75 | MEN1 (0.62) | HTR7HTR1AHTR2AKDM4EALDH1A1 | |
| SCHEMBL10090165 | 0.75 | MEN1 (0.62) | HTR7HTR1AHTR2AKDM4EALDH1A1 | |
| SCHEMBL6526310 | 0.75 | HTR7 (0.65) | HTR7HTR1AHTR2ADRD2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2274056-B1 | BLEACHING AGENT COMPRISING CATIONIC 3,4-DIHYDROISOCHINOLINIUM DERIVATIVES, SPECIFIC ALKANOLAMINES AND HYDROGEN PEROXYDE | HENKEL AG & CO KGAA (DE) | 2012-10-03 | — | — | EP | claimed |
| US-20110146005-A1 | CATIONIC DIHYDROISOQUINOLINIUM DERIVATIVES FOR USE AS BLEACH ACTIVATORS | GROSS WIBKE | 2011-06-23 | — | — | US | claimed |
| US-20110056508-A1 | BLEACHING AGENT COMPRISING CATIONIC 3,4-DIHYDROISOQUINOLINE DERIVATIVES, SPECIAL ALKANOL AMINES AND HYDROGEN PEROXIDE | GROSS WIBKE | 2011-03-10 | — | — | US | claimed |
| US-8025704-B2 | Matting additive for blond hair dyeing | HENKEL AG & CO. KGAA (DE) | 2011-09-27 | — | — | US | disclosed |
| US-20110146005-A1 | CATIONIC DIHYDROISOQUINOLINIUM DERIVATIVES FOR USE AS BLEACH ACTIVATORS | GROSS WIBKE | 2011-06-23 | — | — | US | disclosed |
| US-20110126361-A1 | Matting Additive for Blond Hair Dyeing | MANNECK HARTMUT | 2011-06-02 | — | — | US | disclosed |
| US-20110056508-A1 | BLEACHING AGENT COMPRISING CATIONIC 3,4-DIHYDROISOQUINOLINE DERIVATIVES, SPECIAL ALKANOL AMINES AND HYDROGEN PEROXIDE | GROSS WIBKE | 2011-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110126361-A1 | Matting Additive for Blond Hair Dyeing | LDHB, HMBS, HBB | HTR7 475/4885HTR1A 453/4885HTR2A 1054/4885 |
| US-20110056508-A1 | BLEACHING AGENT COMPRISING CATIONIC 3,4-DIHYDROISOQUINOLINE DERIVATIVES, SPECIAL ALKANOL AMINES AND HYDROGEN PEROXIDE | KRT18, H1-3, H1-2 | HTR7 379/4885HTR1A 715/4885HTR2A 638/4885 |
| US-20110146005-A1 | CATIONIC DIHYDROISOQUINOLINIUM DERIVATIVES FOR USE AS BLEACH ACTIVATORS | KRT18, QDPR, DSG1 | HTR7 1329/4885HTR1A 3054/4885HTR2A 1558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.