Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1023704 | 0.83 | TAS1R3 (0.49) | CES2CES1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL19328352 | 0.81 | KMT2A (0.47) | CES2CES1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL6391071 | 0.78 | TAS1R3 (0.48) | CES2CES1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL10026169 | 0.77 | ALDH1A1 (0.49) | CES2CES1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL19328345 | 0.77 | TSHR (0.52) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5060468 | 0.77 | CES2 (0.50) | CES2CES1SMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL19328370 | 0.75 | HSD11B1 (0.42) | SMN1; SMN2HTTTAS1R3TAS1R1LMNA | |
| SCHEMBL19328379 | 0.75 | CES2 (0.45) | CES2CES1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30859400 | 0.75 | LCK (0.47) | CES2CES1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL5054802 | 0.74 | ALKBH5 (0.47) | CES2CES1SMN1; SMN2HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10080757-B2 | Inhibitors of UDP-galactopyranose mutase | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2018-09-25 | — | — | US | disclosed |
| US-20170258805-A1 | INHIBITORS OF UDP-GALACTOPYRANOSE MUTASE | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2017-09-14 | — | — | US | disclosed |
| US-20170258805-A1 | INHIBITORS OF UDP-GALACTOPYRANOSE MUTASE | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2017-09-14 | — | — | US | disclosed |
| US-20170258805-A1 | INHIBITORS OF UDP-GALACTOPYRANOSE MUTASE | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2017-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170258805-A1 | INHIBITORS OF UDP-GALACTOPYRANOSE MUTASE | UGDH, GALE, UGGT1 | CES2 3013/4885CES1 996/4885SMN1; SMN2 3230/4885 |
| US-10080757-B2 | Inhibitors of UDP-galactopyranose mutase | UGDH, GALE, UGGT1 | CES2 3013/4885CES1 996/4885SMN1; SMN2 3230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.