SCHEMBL799745

SCHEMBL799745

COc1cc(O)cc(O)c1C(=O)CCc1ccc(O)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC5A1 P13866 10/20 0.72
SLC5A2 P31639 8/20 0.72
MAPT P10636 4/20 0.72
SLC28A3 Q9HAS3 3/20 0.72
HPGD P15428 3/20 0.72
HSD17B10 Q99714 3/20 0.72
CYP19A1 P11511 2/20 0.72
MEN1 O00255 2/20 0.72
KMT2A Q03164 2/20 0.72
NFKB1 P19838 2/20 0.72
NFKB2 Q00653 2/20 0.72
RELA Q04206 2/20 0.72
GAA P10253 2/20 0.72
KDM4E B2RXH2 2/20 0.72
CYP3A4 P08684 2/20 0.72
THRB P10828 2/20 0.72
CYP2C9 P11712 2/20 0.72
CYP2C19 P33261 2/20 0.72
SLC16A3 O15427 1/20 0.72
ALDH1A1 P00352 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1938352 0.93 SLC5A1 (0.84) SLC5A1SLC5A2MAPTSLC28A3HPGD
SCHEMBL6398347 0.91 NFKB1 (0.74) SLC5A1SLC5A2MAPTSLC28A3HPGD
SCHEMBL1938569 0.90 SLC5A1 (0.73) SLC5A1SLC5A2MAPTSLC28A3HPGD
SCHEMBL20281260 0.89 SLC5A1 (0.68) SLC5A1SLC5A2MAPTSLC28A3HPGD
SCHEMBL2282039 0.86 NFKB1 (0.83) SLC5A1SLC5A2MAPTSLC28A3HPGD
Asebogenin SCHEMBL4740064 0.85 NFKB1 (0.88) SLC5A1SLC5A2MAPTSLC28A3HPGD
Phloretin SCHEMBL27910960 0.85 SLC5A1 (0.93) SLC5A1SLC5A2MAPTSLC28A3HPGD
Phloretin SCHEMBL38131 0.85 SLC5A1 (1.00) SLC5A1SLC5A2MAPTSLC28A3HPGD
Phloretin SCHEMBL1506325 0.85 SLC5A1 (1.00) SLC5A1SLC5A2MAPTSLC28A3HPGD
SCHEMBL457127 0.84 SLC5A1 (1.00) SLC5A1SLC5A2MAPTSLC28A3HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023169995-A1 SWEETENER COMPOSITIONS FIRMENICH SA (CH) 2023-09-14 WO disclosed
US-9328128-B2 Arylfluorophosphate inhibitors of intestinal apical membrane sodium/phosphate co-transport DUOPHOS (US) 2016-05-03 US disclosed
US-20150080597-A1 ARYLFLUOROPHOSPHATE INHIBITORS OF INTESTINAL APICAL MEMBRANE SODIUM/PHOSPHATE CO-TRANSPORT DUOPHOS 2015-03-19 US disclosed
US-8921343-B2 Arylfluorophosphate inhibitors of intestinal apical membrane sodium/phosphate co-transport DUOPHOS (US) 2014-12-30 US disclosed
US-8431166-B2 Composition comprising the extract of Anemarrhena asphodeloides Bunge or the compounds isolated from the same for preventing and treating lipid metabolism disorder EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUNDATION (KR) 2013-04-30 US disclosed
US-8431166-B2 Composition comprising the extract of Anemarrhena asphodeloides Bunge or the compounds isolated from the same for preventing and treating lipid metabolism disorder EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUNDATION (KR) 2013-04-30 US disclosed
US-20130059822-A1 Arylfluorophosphate Inhibitors of Intestinal Apical Membrane Sodium/Phosphate Co-Transport DUOPHOS (US) 2013-03-07 US disclosed
US-20120070515-A1 Composition Comprising the Extract of Anemarrhena Asphodeloides Bunge or the Compounds Isolated from the Same for Preventing and Treating Lipid Metabolism Disorder EWHA UNIVERSITY- INDUSTRY COLLABORATION FOUNDATION (KR) 2012-03-22 US disclosed
US-20120070515-A1 Composition Comprising the Extract of Anemarrhena Asphodeloides Bunge or the Compounds Isolated from the Same for Preventing and Treating Lipid Metabolism Disorder EWHA UNIVERSITY- INDUSTRY COLLABORATION FOUNDATION (KR) 2012-03-22 US disclosed
US-7777073-B2 Topical delivery system for antiaging and skin whitening agents BIODERM RESEARCH (US) 2010-08-17 US disclosed
US-20090074691-A1 Topical Delivery System for Antiaging and Skin Whitening Agents BIODERM RESEARCH (US) 2009-03-19 US disclosed
US-7427690-B2 Multifunction “crown complexes” from amino acids and peptides for skin and hair restoration BIODERM RESEARCH (US) 2008-09-23 US disclosed
US-20070099886-A1 Multifunction \"Crown Complexes\" from Amino Acids and Peptides for Skin and Hair Restoration BIODERM RESEARCH (US) 2007-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150080597-A1 ARYLFLUOROPHOSPHATE INHIBITORS OF INTESTINAL APICAL MEMBRANE SODIUM/PHOSPHATE CO-TRANSPORT SLC10A2, SLC34A2, SLC34A1 SLC5A1 29/4885SLC5A2 31/4885MAPT 2467/4885
US-20090074691-A1 Topical Delivery System for Antiaging and Skin Whitening Agents TYR, MMP17, MMP1 SLC5A1 4606/4885SLC5A2 4510/4885MAPT 3248/4885
US-20120070515-A1 Composition Comprising the Extract of Anemarrhena Asphodeloides Bunge or the Compounds Isolated from the Same for Preventing and Treating Lipid Metabolism Disorder FABP4, ACACB, LIPC SLC5A1 1311/4885SLC5A2 852/4885MAPT 2597/4885
US-20130059822-A1 Arylfluorophosphate Inhibitors of Intestinal Apical Membrane Sodium/Phosphate Co-Transport SLC10A2, SLC34A2, SLC34A1 SLC5A1 29/4885SLC5A2 31/4885MAPT 2467/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.