Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.38 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3870188 | 0.78 | L3MBTL1 (0.50) | CYP2D6CYP2C9CYP2C19L3MBTL1EPHX1 | |
| SCHEMBL7448019 | 0.76 | FFAR1 (0.57) | CYP2C19FFAR1FFAR4SMN1; SMN2 | |
| SCHEMBL3869724 | 0.75 | MTNR1A (0.49) | TSHRL3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL20512252 | 0.73 | MMP8 (0.43) | CYP1A2CYP2D6CYP2C9TSHRCYP2C19 | |
| SCHEMBL3888886 | 0.73 | CALM1 (0.50) | CYP1A2CYP2C9TSHRCYP2C19FFAR1 | |
| SCHEMBL11135874 | 0.73 | SMN1; SMN2 (0.55) | FFAR1FFAR4SMN1; SMN2MCL1HPGD | |
| SCHEMBL7916098 | 0.73 | ALDH1A1 (0.55) | FFAR1FFAR4SMN1; SMN2NPC1RAB9A | |
| Phenethylcarbamic Acid SCHEMBL249525 | 0.72 | CA12 (0.68) | CA12CA2CA9L3MBTL1EPHX1 | |
| SCHEMBL6722156 | 0.72 | TDP1 (0.46) | CYP1A2CYP2C9TSHRCYP2C19FFAR1 | |
| SCHEMBL6722153 | 0.72 | FFAR1 (0.41) | TSHRFFAR1FFAR4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170281620-A1 | CHEMICALLY AND METABOLICALLY STABLE DIPEPTIDE POSSESSING POTENT SODIUM CHANNEL BLOCKER ACTIVITY | PARION SCIENCES, INC. (US) | 2017-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170281620-A1 | CHEMICALLY AND METABOLICALLY STABLE DIPEPTIDE POSSESSING POTENT SODIUM CHANNEL BLOCKER ACTIVITY | CACNA1B, SCN1B, KCNB1 | CYP1A2 1686/4885CYP2D6 602/4885CYP2C9 920/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.