Sugi Predict

Sugi Predict / Compounds / SCHEMBL194095

SCHEMBL194095

SCHEMBL194095

C=C(CS(=O)(=O)c1ccccc1)C(=O)NC

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HSD11B1 P28845 7/20 0.53
▸ KMT2A Q03164 2/20 0.47
▸ POLB P06746 1/20 0.47
▸ ALDH1A1 P00352 3/20 0.46
▸ TP53 P04637 1/20 0.46
▸ HTT P42858 1/20 0.46
▸ HSD17B10 Q99714 1/20 0.46
▸ HDAC1 Q13547 1/20 0.46
▸ HDAC2 Q92769 1/20 0.46
▸ PSIP1 O75475 1/20 0.46
▸ MMP2 P08253 2/20 0.45
▸ MMP7 P09237 2/20 0.45
▸ MMP14 P50281 2/20 0.45
▸ RECQL P46063 2/20 0.44
▸ CA12 O43570 1/20 0.44
▸ CA2 P00918 1/20 0.44
▸ CA9 Q16790 1/20 0.44
▸ MEN1 O00255 1/20 0.44
▸ NPC1 O15118 1/20 0.44
▸ RAB9A P51151 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5491920 0.80 HSD11B1 (0.56) HSD11B1KMT2APOLBALDH1A1TP53
SCHEMBL3182773 0.80 HSD11B1 (0.53) HSD11B1KMT2APOLBALDH1A1TP53
SCHEMBL7922108 0.79 KMT2A (0.62) HSD11B1KMT2APOLBALDH1A1TP53
SCHEMBL24106342 0.76 MAPT (0.53) HSD11B1KMT2APOLBALDH1A1HTT
Hydrochloric Acid SCHEMBL30116899 0.76 HSD11B1 (0.51) HSD11B1KMT2APOLBALDH1A1TP53
SCHEMBL6654245 0.74 POLB (0.61) HSD11B1KMT2APOLBALDH1A1TP53
SCHEMBL5080063 0.74 HSD11B1 (0.58) HSD11B1KMT2APOLBALDH1A1TP53
SCHEMBL28298913 0.73 HSD11B1 (0.55) HSD11B1KMT2APOLBALDH1A1TP53
SCHEMBL3651298 0.72 HSD11B1 (0.66) HSD11B1KMT2APOLBALDH1A1TP53
SCHEMBL28873529 0.72 HSD11B1 (0.51) HSD11B1KMT2APOLBALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9365515-B2 Oxime ester photoinitiators BASF SE (DE) 2016-06-14 — — US disclosed
US-9310677-B2 Polymerizable composition comprising an oxime sulfonate as thermal curing agent BASF (DE) 2016-04-12 — — US disclosed
US-20140334027-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2014-11-13 — — US disclosed
US-20130308219-A1 POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT BASF SE (DE) 2013-11-21 — — US disclosed
US-8524425-B2 Oxime ester photoinitiators BASF SE (DE) 2013-09-03 — — US disclosed
US-8349548-B2 Oxime ester photoinitiators BASF SE (DE) 2013-01-08 — — US disclosed
US-8148358-B2 Blue colour filters with enhanced contrast BASF SE (DE) 2012-04-03 — — US disclosed
US-20120038996-A1 PHOTORESIST COMPOSITIONS BASF SE (DE) 2012-02-16 — — US disclosed
EP-2411430-A1 PHOTORESIST COMPOSITION BASF SE (DE) 2012-02-01 — — EP disclosed
EP-2285836-B1 PHOTOINITIATOR MIXTURES BASF SE (DE) 2012-01-18 — — EP disclosed
US-20100317819-A1 SURFACE-MODIFIED NANOPARTICLES COMPRISING A CATIONIC COLORANT FOR USE IN COLOR FILTERS CIBA CORPORATION (US) 2010-12-16 — — US disclosed
US-20100227199-A1 Blue Colour Filters with Enhanced Contrast CIBA CORPORATION 2010-09-09 — — US disclosed
US-20100136467-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2010-06-03 — — US disclosed
US-20100086881-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2010-04-08 — — US disclosed
US-7648738-B2 for photopolymerization; photography, relief imaging; color filters CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-01-19 — — US disclosed
US-20090293769-A1 BLUE PHTHALOCYANINE PIGMENT COMPOSITION AND ITS PREPARATION CIBA CORPORATION (US) 2009-12-03 — — US disclosed
US-20080206658-A1 Compositions Containing Anthraquinone Dyes HUNTSMAN INTERNATIONAL LLC (US) 2008-08-28 — — US disclosed
US-20080095950-A1 Compositions Containing Phthalocyanine Dyes HUNTSMAN INTERNATIONAL LLC (US) 2008-04-24 — — US disclosed
US-20060241259-A1 Oxime ester photoinitiators with heteroaromatic groups CIBA CORPORATION 2006-10-26 — — US disclosed
US-5571642-A LIGHT SENSITIVE ELEMENTS WITH CHEMICAL RESISTANCE FUJI PHOTO FILM CO., LTD. (JP) 1996-11-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100136467-A1 OXIME ESTER PHOTOINITIATORS CHRM4, NR2E3, CYP3A4 HSD11B1 614/4885KMT2A 924/4885POLB 2215/4885
US-20100086881-A1 OXIME ESTER PHOTOINITIATORS CYP3A4, CHRM1, PPOX HSD11B1 885/4885KMT2A 849/4885POLB 693/4885
US-20120038996-A1 PHOTORESIST COMPOSITIONS HAAO, CBR3, AKR1B10 HSD11B1 1031/4885KMT2A 464/4885POLB 2421/4885
US-20100227199-A1 Blue Colour Filters with Enhanced Contrast NR1H4, NR1D1, NR1D2 HSD11B1 491/4885KMT2A 3948/4885POLB 3843/4885
US-20100317819-A1 SURFACE-MODIFIED NANOPARTICLES COMPRISING A CATIONIC COLORANT FOR USE IN COLOR FILTERS CD63, CD59, ITGAM HSD11B1 4845/4885KMT2A 703/4885POLB 4460/4885
US-20080095950-A1 Compositions Containing Phthalocyanine Dyes ZKSCAN2, INCENP, CRY2 HSD11B1 1109/4885KMT2A 900/4885POLB 4168/4885
US-20140334027-A1 OXIME ESTER PHOTOINITIATORS CBR3, OR10J3, CHRM1 HSD11B1 341/4885KMT2A 2647/4885POLB 1486/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.