SCHEMBL19422849

SCHEMBL19422849

CC(C)(OC1C(CO)OC(O)C(N)C1O)C1OC(CO)C(O)C(O)C1N

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.38
▸ MAPT P10636 1/20 0.37
▸ TSHR P16473 2/20 0.34
▸ HSD17B10 Q99714 1/20 0.34
▸ LMNA P02545 1/20 0.33
▸ KDM4E B2RXH2 1/20 0.33
▸ ALOX15 P16050 1/20 0.33
▸ MEN1 O00255 2/20 0.33
▸ LRAT O95237 1/20 0.33
▸ TRPV1 Q8NER1 1/20 0.33
▸ BLM P54132 1/20 0.32
▸ RECQL P46063 1/20 0.32
▸ TDP1 Q9NUW8 1/20 0.32
▸ GJA1 P17302 1/20 0.32
▸ GJB2 P29033 1/20 0.32
▸ CYP2C9 P11712 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ MAPK1 P28482 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19860207 0.82 L3MBTL1 (0.36) L3MBTL1MAPTTSHRHSD17B10MEN1
SCHEMBL22652633 0.77 L3MBTL1 (0.33) L3MBTL1MAPT
Glucosamine SCHEMBL3802633 0.77 PYGB (0.42) L3MBTL1MAPTTSHRHSD17B10LMNA
Glucosamine SCHEMBL28095460 0.77 LGALS1 (0.42) LMNAKDM4EALOX15
Glucosamine SCHEMBL29993892 0.77 LGALS1 (0.42) LMNAKDM4EALOX15
Glucosamine SCHEMBL24336697 0.76 LGALS1 (0.45) TSHRHSD17B10LMNAKDM4EALOX15
Glucosamine SCHEMBL21240813 0.76 LGALS1 (0.45) TSHRHSD17B10LMNAKDM4EALOX15
Glucosamine SCHEMBL13985995 0.76 LGALS1 (0.45) TSHRHSD17B10LMNAKDM4EALOX15
Glucosamine SCHEMBL22137006 0.76 LGALS1 (0.45) TSHRHSD17B10LMNAKDM4EALOX15
Glucosamine SCHEMBL22748633 0.76 LGALS1 (0.45) TSHRHSD17B10LMNAKDM4EALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11207343-B2 Compositions and therapeutic methods AYUVIS RESEARCH, INC. (US) 2021-12-28 — — US disclosed
US-10624984-B2 Aptamer-modified polymeric materials for the binding of factors in a wound environment KCI LICENSING, INC. (US) 2020-04-21 — — US disclosed
US-20200101103-A1 REINFORCEMENT OF MUCUS BARRIER PROPERTIES Cirqle Biomedical Contraception Ivs (DK) 2020-04-02 — — US disclosed
US-20180042825-A1 MICROCAPSULE COMPOSITIONS WITH HIGH PERFORMANCE INTERNATIONAL FLAVORS & FRAGRANCES INC. 2018-02-15 — — US disclosed
US-20170281667-A1 NOVEL COMPOSITIONS AND THERAPEUTIC METHODS AYUVIS RESEARCH, INC. 2017-10-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11207343-B2 Compositions and therapeutic methods RB1, TNF, FLT1 L3MBTL1 3218/4885MAPT 859/4885TSHR 2174/4885
US-20180042825-A1 MICROCAPSULE COMPOSITIONS WITH HIGH PERFORMANCE UMPS, AUP1, PFAS L3MBTL1 3667/4885MAPT 1192/4885TSHR 4241/4885
US-20170281667-A1 NOVEL COMPOSITIONS AND THERAPEUTIC METHODS RB1, CD47, FLT1 L3MBTL1 3066/4885MAPT 984/4885TSHR 2494/4885
US-10624984-B2 Aptamer-modified polymeric materials for the binding of factors in a wound environment SDF4, PCLAF, CCL2 L3MBTL1 1079/4885MAPT 4360/4885TSHR 3192/4885
US-20200101103-A1 REINFORCEMENT OF MUCUS BARRIER PROPERTIES MUC1, FUT5, FUT8 L3MBTL1 4469/4885MAPT 3691/4885TSHR 2005/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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